Kim et al. [30]

2004

Cross- sectional study

US (San Francisco)

Children

Ÿ Traffic intensity (90,000 - 210,000 veh/day)

Ÿ Distance (<300 m downwind)

Ÿ Pollutants measured

­ PM10

­ PM2.5

­ BC

­ NOx

­ NO2

­ NO

Ÿ RD

­ Asthma

­ Bronchitis

Ÿ Observation of difference concentrations between schools nearby versus more distant (or upwind) from major roads

Ÿ Association between respiratory symptoms and traffic related pollutants

Ÿ Findings support the hypothesis that TRAP is associated with respiratory symptoms

Lindgren et al. [31]

2009

Cross- sectional study

Southern Sweden

Adults (18 - 77 years)

Ÿ Traffic intensity (0 - 1 cars/min; 2 - 5 cars/min; 6 - 10 cars/min and >10 cars/min based upon 24-hour mean levels)

Ÿ Pollutants measured

­ NOx modeled exposure)

Ÿ RS

­ Asthma symptoms

­ Chronic bronchitis symptoms

Ÿ RD

­ Asthma

­ COPD

­ CBE

Ÿ Living close to traffic (within 100 m of a road with >10 cars/minute) was associated with prevalence of asthma diagnosis and COPD diagnosis, and symptoms of asthma and bronchitis.

Ÿ Annual average NOx was associated with COPD diagnosis and symptoms of asthma and chronic bronchitis

Hoek et al. [32]

2002

Cohort study

Netherlands

Adults (55 - 69 years)

Ÿ Distance

Ÿ Pollutants measured

­ BC

­ NO2

Ÿ RD

­ Lung cancer

­ Cardio- pulmonary diseases

Ÿ Cardiopulmonary mortality was associated with living near a major road.

Ÿ Long-term exposure to traffic-related air pollution may shorten life expectancy

Migliore et al. [33]

2009

Cross- sectional study

Italy

Children (6 - 7 years) and adolescents (13 - 14 years)

Ÿ Traffic intensity

Ÿ RS

­ Asthma symptoms

­ Cough or phlegm

Ÿ Traffic density was weakly associated with asthma symptoms but there was a stronger association with cough or phlegm.

Ÿ Children living in zones with intense traffic are at higher risk for respiratory effects.