Pre-op

6 mo-post

2 yr-post

P

Prothrombin time (s)

13.18 ± 0.50

13.30 ± 0.54

4.01 ± 0.35

0.951

Fibrinogen (g/L)

3.13 ± 0.17

3.26 ± 0.17

2.88 ± 0.20

0.341

Activated partial

thromboplastin time (s)

29.55 ± 1.13

30.94 ± 0.98

32.63 ± 1.22

0.169