Item

Group

Pre-treatment

6 months pro-treatment

1 year pro-treatment

t

P

BMD

A

−2.96 ± 0.18

−2.94 ± 0.17^a

−2.62 ± 0.20^b

−1.45/−8.52

0.16 ^a/<0.05 ^b

(SD)

B

−2.94 ± 0.22

−2.90 ± 0.23^a

−2.32 ± 0.19^b

−1.83/−0.29

0.08 ^a/<0.05 ^b

C

−2.96 ± 0.19

−2.92 ± 0.20^a

−2.06 ± 0.23^b

−1.93/−9.80

0.06 ^a/<0.05 ^b

PINP

A

58.57 ± 1.68

44.83 ± 12.35^a

43.10 ± 10.62^b

−12.38/−13.42

<0.05 ^a/<0.05 ^b

(g/L)

B

59.76 ± 1.83

72.34 ± 15.16^a

68.73 ± 13.72^b

9.89/5.34

<0.05 ^a/<0.05 ^b

C

58.85 ± 1.83

65.74 ± 8.98^a

64.23 ± 14.61^b

6.72/5.89

<0.05 ^a/<0.05 ^b

β-

A

0.55 ± 0.32

0.29 ± 0.08^a

0.26 ± 0.13^b

−0.32/−0.35

<0.05 ^a/<0.05 ^b

CTX

B

0.53 ± 0.19

0.43 ± 0.12^a

0.38 ± 0.21^b

−0.13/−0.16

<0.05 ^a/<0.05 ^b

(g/L)

C

0.54 ± 0.24

0.39 ± 0.31^a

0.32 ± 0.14^b

−0.19/−0.21

<0.05 ^a/<0.05 ^b