Drinking Water

Urine output

ml/kg BW

ml/kg BW

Time

9 AM to 4 PM

4 PM to 9 AM

24 h

24 h

Study 1: CO vs Supplement 50 ml/d

Males (n = 4)

CO

47 ± 11

20 ± 7

67 ± 18

40 ± 11

D50

55 ± 6*

31 ± 14

87 ± 18*

59 ± 6*

Females (n = 4)

CO

40 ± 9

49 ± 10

88 ± 19

70 ± 28

D50

58 ± 11*

50 ± 21

108 ± 12*

97 ± 11*

All dogs (n = 8)

CO

43 ± 10

34 ± 17

78 ± 20

55 ± 25

D50

57 ± 9*

40 ± 20

97 ± 18*

78 ± 22*

Study 2: CO vs Supplement 70 ml/d

Males (n = 2)

CO

37 ± 5

16 ± 2

54 ± 6

33 ± 8

D70

51 ± 6*

23 ± 10

74 ± 4

51 ± 2*

Females (n = 2)

CO

47 ± 5

35 ± 19

82 ± 23

59 ± 25

D70

54 ± 1

42 ± 26

95 ± 26

74 ± 20*

All dogs (n = 4)

CO

42 ± 7

25 ± 15

68 ± 21

46 ± 22

D70

52 ± 3

32 ± 19

84 ± 20*

63 ± 18*