Mean ± SD

p values

TB

(N = 13 and 25^▲)

IPTB

(n = 9 and 9^▲)

CC

(n = 5 and 36^▲)

IPCC

(n = 9 and 38^▲)

IPTB × TB

IPTB × IPCC

IPTB × CC

TB × IPCC

TB × CC

IPCC × CC

38kDa/CFP-10

IL-1beta

778 ± 715.5*

1211 ± 2572

1415 ± 1208

692.6 ± 494.4

0.191

0.254

0.189

0.973

0.298

0.297

IL-2

34 ± 36.4

35 ± 43.9

31.7 ± 23.5

34.6 ± 32.5

0.703

0.716

0.673

0.810

0.792

0.944

IL-4

46.1 ± 40.6

56.3 ± 73.7

28.8 ± 21.5

26.2 ± 33.4

0.963

0.175

0.508

0.882

0.388

0.429

IL-5

40.5 ± 29.1*

49.2 ± 38.7

30.6 ± 28.6

19.7 ± 22.8

0.610

0.124

0.350

0.084

0.477

0.646

IL-6

1456 ± 1060

2024 ± 2008

1544 ± 1127

1670 ± 1062

0.331

0.812

0.677

0.366

0.944

0.566

IL-7

297 ± 135.3***

201.3 ± 200

102.3 ± 154.3

90.3 ± 135.5

0.067

0.421

0.772

0.004

0.037

0.537

IL-8

2098 ± 2221

3311 ± 2366

523.6 ± 416

1022 ± 1602

0.244

0.049

0.038

0.156

0.089

0.497

IL-10

500.5 ± 311.3**

381.2 ± 386.6

392.8 ± 143.4

372.6 ± 181**

0.402

0.775

0.629

0.348

0.580

0.629

IL-12p70

728.4 ± 678.9

402.4 ± 392.4

128.2 ± 286.5

174.8 ± 354.3

0.188

0.294

0.286

0.01

0.021

0.835

IL-13

83.8 ± 43

142 ± 150.2

47.2 ± 12.3

62.6 ± 51.7

0.480

0.195

0.089

0.360

0.185

0.572

IL-17A

681.6 ± 507.7

670.3 ± 571.7

277.1 ± 282.6

344.3 ± 296.6

0.753

0.2

0.174

0.065

0.06

0.740

IFN-gamma^▲

440 ± 392.3

262.3 ± 270

15.7 ± 39.7

3.9 ± 11.3

0.208

>0.001

>0.001

>0.001

>0.001

0.992

TNF-alpha

221.6 ± 120.3

229 ± 127.7

155 ± 85

249 ± 362

0.986

0.281

0.251

0.396

0.376

0.766

G-CSF

367.3 ± 223.5*

411.6 ± 760.2

357.6 ± 200.8

217.3 ± 119.9**

0.129

0.651

0.311

0.069

0.995

0.436

GM-CSF

206.6 ± 713.6

265.7 ± 673.6

3.69 ± 0.93

141.2 ± 301.7

0.193

0.105

0.328

0.812

0.999

0.670

MCP-1 (CCL2)

467.7 ± 241.1

673 ± 579.7

333 ± 274.6

546 ± 266.4

0.707

0.842

0.410

0.481

0.360

0.181

MIP-1beta (CCL4)

1092 ± 1269*

1348 ± 1876

479.4 ± 244.6

693.7 ± 401.2

0.299

0.729

0.677

0.555

0.112

0.410

ESAT-6/CFP-10

IL-1beta

282.2 ± 272.4

138.3 ± 154.5

930.8 ± 427.2

398.6 ± 323.4

0.068

0.023

0.004

0.402

0.006

0.029

IL-2

27.7 ± 23.9

49.2 ± 72.4

25.3 ± 21.5

20.4 ± 21.8

0.831

0.456

0.875

0.561

0.972

0.572

IL-4

28.9 ± 29

43.4 ± 31

25.7 ± 15.2

18.5 ± 18.4

0.248

0.097

0.361

0.495

0.779

0.408

IL-5

19.5 ± 18.1

77 ± 71.5

33.9 ± 14.3

33.2 ± 25.4

>0.001

0.085

0.125

0.197

0.127

0.812

IL-6

1377 ± 821.1

1390 ± 1105

1341 ± 336.7

1343 ± 986.4

0.882

0.975

0.722

0.882

0.552

0.603

IL-7

128.2 ± 176

199.4 ± 216.3

189.3 ± 164.4

146 ± 146

0.323

0.674

0.772

0.332

0.293

0.880

IL-8

3445 ± 2313

4100 ± 2172

2697 ± 1914*

3058 ± 2220*

0.604

0.509

0.262

0.834

0.501

0.897

IL-10

148.2 ± 108.4

184.8 ± 132.4

246.7 ± 162.8

122.4 ± 122.5

0.479

0.194

0.580

0.238

0.298

0.089

IL-12p70

509.8 ± 595.3

407.2 ± 422.3

128.2 ± 286.4

148.1 ± 238

0.745

0.181

0.237

0.109

0.157

0.999

IL-13

70.4 ± 101

170.6 ± 157.2

70.7 ± 28.3

51.4 ± 36.4

0.033

0.029

0.409

0.699

0.231

0.201

IL-17A

392.7 ± 364.3

644 ± 764.2

372.8 ± 193

237.5 ± 309.1

0.700

0.313

0.984

0.375

0.999

0.262

IFN-gamma^▲

448.3 ± 481.4

420.4 ± 634.8

14.6 ± 42.2

7.9 ± 24.3

0.474

>0.001

>0.001

>0.001

>0.001

0.277

TNF-alpha

137.6 ± 80

191 ± 129

120.5 ± 49

119.3 ± 55.3

0.253

0.160

0.286

0.937

0.882

0.999

G-CSF

218.2 ± 185.2

173.9 ± 177.6

348.2 ± 198

88.3 ± 54.5

0.522

0.423

0.119

0.045

0.074

0.006

GM-CSF

173.2 ± 467.6

218.5 ± 572

3.69 ± 0.93

11.8 ± 25.5

0.019

0.026

0.055

0.999

0.999

0.999

MCP-1 (CCL2)

497.5 ± 293.2

821.8 ± 812.8

230.2 ± 201.3

392.2 ± 179.6

0.390

0.160

0.141

0.348

0.071

0.080

MIP-1beta (CCL4)

505.3 ± 346.1

459.2 ± 361.8

503.4 ± 444.8

442.3 ± 384.4

0.706

0.777

0.824

0.402

0.832

0.972