| Clinical trials on EDS and Parkinson’s Disease | ||
| Name of paper | Author(s) | Journal/Issue |
| A randomized trial of a low-dose Rasagiline and Pramipexole combination (P2B001) in early Parkinson’s disease | Olanow CW, Kieburtz K, Leinonen M, Elmer L, Giladi N, Hauser RA, Klepiskaya OS, et al. | Movement Disorders 2016, 32: 783-789 |
| Acupuncture in the treatment of fatigue in Parkinson’s disease: A pilot, randomized, controlled, study | Kong KH, Ng HL, Li W, Ng DW, Tan SI, Tay Ky, Au WL et al. | Brain Behavior 2017, 8(1): e00897 |
| Bright light therapy with a head-mounted device for anxiety, depression, sleepiness and fatigue in patients with Parkinson’s disease | Raymackers J, Andrade M, Baey E, Vanneste M, Evrard F | Acta Neurologica Belgica 2019, 119: 607-613 |
| Caffeine as symptomatic treatment for Parkinson disease (Café-PD): A randomized trial. | Postuma RB, Anang J, Pelletier A, Joseph L, Moscovich M, Grimes D, Furtado S, et al. | Neurology. 2017, 89(17): 1795-1803 |
| Daytime sleepiness may be an independent symptom unrelated to sleep quality in Parkinson’s disease | Liguori C, Mercuri NB, Albanese M, Olivola E, Stefani A, Pierantozzi M | Journal of Neurology 2019 Mar, 266(3): 636-641 |
| Effects of rotigotine transdermal patch in patients with Parkinson’s disease presenting with non-motor symptoms—results of a double-blind, randomized, placebo-controlled trial | Antonini A, Bauer L, Dohin E, Oertel WH, Rascol O, Reichmann H, Schmid M et al. | European Journal of Neurology 2015, 22(10): 1400-1407 |
| Effects of transcranial direct current stimulation on executive function in Parkinson’s disease | Doruk D, Gray Z, Bravo GL, Pascual-Leone A, Fregni F. | Neuroscience Letters 2014, 582: 27-31 |
| Homotaurine in Parkinson’s disease | Ricciardi L, De Nigris F, Specchia A, Fasano A | Neurological Sciences 2015, 36: 1581-1587 |
| Impact of inability to turn in bed assessed by a wearable three-axis accelerometer on patients with Parkinson’s disease | Uchino K, Shiraishi M, Tanaka K, Akamatsu M, Hasegawa Y | PLoS One. 2017, 12(11): e0187616 |
| Low-fat versus ketogenic diet in Parkinson’s disease: A pilot randomized controlled trial | Phillips MCL, Murtagh DKJ, Gilbertson LJ, Asztely FJS, Lynch CDP | Movement Disorders 2018, 33(8): 1306-1314 |
| Low-frequency versus high-frequency stimulation of the pedunculopontine nucleus area in Parkinson’s disease: a randomised controlled trial | Nosko D, Ferraye MU, Fraix V, Goetz L, Chabardès S, Pollak P, Debû B | Journal of Neurology Neurosurgery and Psychiatry 2015, 86: 674-679 |
| Rasagiline improves polysomnographic sleep parameters in patients with Parkinson’s disease: a double-blind, baseline-controlled trial | Schrempf W, Fauser M, Wienecke M, Brown S, Maaß A, Ossig C, Otto K, et al. | European Journal of Neurology 2018, 25: 672-679 |
| Repeated sessions of transcranial direct current stimulation evaluation on fatigue and daytime sleepiness in Parkinson’s disease | Forogh B, Rafiei M, Arbabi A, Motamed MR, Madani SP, Sajadi S | Neurological Sciences 2017, 38: 249-254 |
| Sodium Oxybate for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson Disease: A Randomized Clinical Trial | Büchele F, Hackius M, Schreglmann SR, Omlor W, Werth E, Maric A, Imbach LL et al. | JAMA Neurology 2018, 75(1): 114-118 |
| Sublingual apomorphine (APL-130277) for the acute conversion of OFF to ON in Parkinson’s disease | Hauser RA, Olanow CW, Dzyngel B, Bilbault T, Shill H, Isaacson S, Dubow J, et al. | Movement Disorders 2016, 31: 1366-1372 |
| Timed Light Therapy for Sleep and Daytime Sleepiness Associated with Parkinson Disease: A Randomized Clinical Trial | Videnovic A, Klerman EB, Wang W, Marconi A, Kuhta T, Zee PC | JAMA Neurology 2017, 74(4): 411-418 |
| Zonisamide improves wearing-off in Parkinson’s disease: A randomized, double-blind study | Murata M, Hasegawa K, Kanazawa I, Fukasaka J, Kochi K, Shimazu R; Japan Zonisamide on PD Study Group | Movement Disorders 2015, 30(10): 1343-1350 |