| Parameter | Conventional therapy (n = 20) | Levodopa/carbidopa intestinal gel continuous administration (n = 20) | p-value |
| Comorbidities | 4 (20%) | - | 0.007 |
| Diabetes | 4 (20%) | 5 (25%) | 0.001 |
| Hypertension | 7 (35%) | 6 (30%) | 0.027 |
| Osteoporosis | 5 (25%) | 8 (40%) | 0.027 |
| Previous depression | 5 (25%) | - | 0.025 |
| Ischemic cardiomyopathy | - | 8 (40%) | 0.371 |
| Anemia | - | 5 (25%) | 0.025 |
| Camptocormia | - | 10 (50%) | 1 |