Compounds

Activity IC₅₀ (µM)^a

Toxicity IC₅₀

Vero cells (µM)^b

Selectivity index^c

Chlorhexidine digluconate

5.33 ± 3

147.34 ± 1.7

27.6

1

91.3 ± 4.1

100.2 ± 2.3

1.09

2

134.3 ± 1.2

156.7 ± 3.5

1.16

3

3.5 ± 0.5

99.3 ± 1.2

28.3

4

343.5 ± 4.6

100.5 ± 6.9

0.3

5

11.4 ± 1.2

296.3 ± 3.6

26

6

26.7 ± 0.5

685.4 ± 8.6

25.7

7

36.9 ± 0.7

327.53 ± 3.6

8.87

8

783.9 ± 1.2

256.4 ± 38.2

0.33

9

186.3 ± 0.8

846.8 ± 22.9

4.54

10

278 ± 0.4

321.9 ± 40.9

1.15