All liver patients

(n = 29)

PBC

(n = 17)

Non-PBC

(n = 12)

Controls

(n = 21)

p†

Age, years

56 ± 11.1

57.5 ± 10.2

52.7 ± 11.7

46.8 ± 7.6

0.05

Sex, M/F

5/24

0/17

5/7

8/13

---

BMI, kg/m²

24.3 ± 4.63

23.9 ± 4.1

24.8 ± 5.3

28 ± 4.7

0.05

FVC, L

2.58 ± 0.83

2.28 ± 0.61

2.87 ± 0.96

3.81 ± 0.85

<0.02

FVC, % pred.

84.1± 20.6

83.1 ± 18.6

86 ± 15.6

106.2 ± 10.3

<0.01

FEV1, L

2.05 ± 0.72

1.81 ± 0.45

2.30 ± 0.67

3.22 ± 0.67

<0.02

FEV1, % pred.

86.4 ± 19.7

83.1 ± 18.6

88.8 ± 16.7

113.1 ± 13.4

<0.01

FEV1/FVC, %

80.8 ± 9.2

80.7 ± 11.1

81.1 ± 5.9

84.5 ± 3.5

NS

FEF50, % pred.

82 ± 28.5

78.2 ± 32.3

87.4 ± 23

121.7 ± 23.3

<0.01

TLC, L

4.11 ± 1

4.01 ± 0.82

4.18 ± 1.03

5.48 ± 0.97

<0.01

TLC, % pred.

90.5 ± 13.9

89 ± 16.9

92 ± 10

102.5 ± 8

<0.01

FRC, L

2.14 ± 0.47

2.15 ± 0.51

2.12 ± 0.46

2.7 ± 0.61

<0.02

FRC, % pred.

84 ± 17

82.2 ± 16.2

85.8 ± 17.1

90.2 ± 15.2

NS

RV, L

1.37 ± 0.43

1.43 ± 0.41

1.28 ± 0.42

1.59 ± 0.31

0.02

RV, % pred.

87.8 ± 25.3

89.2 ± 23

86 ± 27.5

90.5 ± 15.7

NS

RV/TLC, %

33.6 ± 9.6

35.3 ± 6.8

32.3 ± 11

29.3 ± 4.4

0.05

DLCO, ml/min/mm Hg

12.5 ± 7.2

12 ± 6.7

13.5 ± 7.9

24.5 ± 5.5

0.01

DLCO, %pred.

61.8 ± 28.3

58.1 ± 29.9

68.4 ± 23.9

86.9 ± 23.2

<0.01

DL/VA

3.87 ± 1.15

3.67 ± 1.05

4.12 ± 1.23

4.56 ± 0.64

0.02

DL/VA, % pred.

78.9 ± 17.1

75.7 ± 14.8

82.8 ± 18.8

88.9 ± 15.7

0.01