MMRC 0

MMRC 1

MMRC 2

MMRC 3

MMRC 4

p-value

N (total = 136)

11

12

16

44

53

Age

61 ± 11

65 ± 10

61 ± 6

63 ± 10

60 ± 19

0.79

Sex, M (%)

55

75

56

73

62

0.40

BMI (kg/m²)

24 ± 5

23 ± 3

29 ± 5

26 ± 6

30 ± 9

5.7E−07

GOLD A (n, %)

5 (45.5)

3 (25)

2 (12.5)

0

0

GOLD B (n, %)

5 (45.5)

8 (66.7)

11 (68.5)

17 (38.6)

2 (3.8)

GOLD C (n, %)

1 (9)

0

2 (12.5)

17 (38.6)

8 (15.1)

GOLD D (n, %)

0

1 (8.3)

1 (6.5)

10 (22.7)

43 (81.1)

tEFL (%)

0 (0 - 65)

43.0 (0 - 76.8)

81.1 (62.1 - 100)

56 (0 - 81)

83 (56 - 100)

0.02

FEV1 (% pred)

82 ± 21

72 ± 16

56 ± 16

64 ± 20

52 ± 20

1.9E−13

FVC (% pred)

103 ± 18

91 ± 15

76 ± 16

83 ± 17

73 ± 22

3.0E−08

FEV1/FVC (%)

57 ± 9

56 ± 9

53 ± 10

54 ± 10

51 ± 11

1.9E−06

TLC (% pred)

115 ± 14

112 ± 16

107 ± 15

112 ± 19

105 ± 19

0.37

FRC (% pred)

122 ± 23

124 ± 25

119 ± 30

128 ± 27

128 ± 32

0.52

Slow VC (% pred)

104 ± 17

95 ± 16

80 ± 13

85 ± 18

76 ± 19

5.0E−07

RV (% pred)

129 ± 40

136 ± 34

149 ± 43

150 ± 46

155 ± 45

0.0052

FRC/TLC (%)

61 ± 9

64 ± 7

62 ± 9

65 ± 8

66 ± 9

0.54

RV/TLC (%)

41 ± 11

45 ± 9

50 ± 9

49 ± 10

53 ± 10

3.8E−06

IC (% pred)

103 ± 19

91 ± 19

90 ± 19

88 ± 21

81 ± 23

0.18

IC/TLC (%)

41 ± 10

36 ± 7

38 ± 9

35 ± 8

35 ± 9

0.54

DLCO (% pred)

92 ± 19

84 ± 13

77 (72 - 101)

76 ± 21

60 ± 24

0.0017