Variable | HbSC | HbSS | HbAA | SS versus SC | SS versus AA | SC versus AA | |||
χ2 | P-value | χ2 | P-value | χ2 | P-value | ||||
Total pregnancies (n) | 66 | 98 | 160 |
|
|
|
|
|
|
Pregnancy outcome, n (%) |
|
|
|
|
|
|
|
|
|
Miscarriage | 0 (0) | 4 (4.1) | 0 (0) | - | - | - | - | - | - |
Stillbirth | 6 (9.1) | 20 (20.4) | 2 (1.3) | 3.79 | 0.05 | 28.6 | 1.43 | 8.41 | 0.004 |
Live birth | 60 (90.9) | 74 (75.5) | 158 (98.7) | 4.2 | 0.08 | 36.2 | <0.0001 | 8.31 | 0.003 |
Early neonatal death | 2 | 3 | 3 | 0.05 | 0.82 | 0.93 | 0.34 | 0.39 | 0.53 |
Mode of delivery (live birth) |
|
|
|
|
|
|
|
|
|
Vaginal | 43 (71.9) | 58 (78.4) | 145 (91.8) | 43.81 | 0.54 | 8.26 | 0.004 | 14.81 | <0.0001 |
Caesarean section | 17 (28.1) | 16 (21.6) | 13 (8.2) |
|
|
|
|
|
|
Outcome of live birth (n) | 60 | 74 | 158 |
|
|
|
|
|
|
Birthweight |
|
|
|
|
|
|
|
|
|
Mean ± SD | 2.9 ± 0.6 | 2.3 ± 0.4 | 3.2 ± 0.7 | - | <0.0001 | - | 0.0007 | - | <0.0001 |
Weight < 2.5 kg, n (%) | 24 (40) | 10 (13.5) | 8 (5.1) | 12.28 | <0.0001 | 5.03 | 0.02 | 42.38 | <0.0001 |
Apgar score < 7 at 5 minutes | 8 (13.3) | 6 (8.1) | 14 (8.9) | 0.97 | 0.33 | 0.03 | 0.84 | 0.96 | 0.33 |
Gestational age at delivery |
|
|
|
|
|
|
|
|
|
Preterm (<37 weeks) | 20 (33.3) | 21 (21.4) | 19 (11.9) | 0.38 | 0.54 | 9.45 | 0.002 | 13.44 | <0.0001 |
Mean ± SD | 37.6 ± 1.4 | 37.1 ± 1.2 | 38.6 ± 2.1 | - | 0.03 | - | <0.0001 | - | 0.0008 |