Clinical Feature

HC

MS

MS-Untreated

p-value Untreated vs HC

MS-Treated Alemtuzumab

p-value treated vs HC

p-value untreated vs treated

p-value Chi squared

N

22

22

12

-

10

-

-

-

Age (years)―mean ± SD

39.4 ± 12.5

41.1 ± 15.2

46.5 ± 17.0

0.444

34.7 ± 10.0

1.0

0.138

-

Gender (female)―N (%)

6 (73)

17 (77)

8 (67)

-

9 (90)

-

-

0.426

Gender (male)―N (%)

16 (27)

5 (23)

4 (33)

-

1 (10)

-

-

Age onset (years)― mean ± SD

-

32.6 ± 10.7

37.2 ± 10.1

-

27.2 ± 9.2

-

0.004

EDSS―mean ± SD

-

2.4 ± 2.6

1.8 ± 2.3

-

3±2.9

-

0.434

Total number of relapses―mean ± SD

-

3.4 ± 2.7

3.4 ± 3.3

-

3.3 ± 1.9

-

0.833