ECOG performance status category: (n = 266)

ECOG 0

1.00 (Reference)

-

1.00 (Reference)

-

ECOG 1

1.04 (0.4 - 2.5)

0.920

1.18 (0.5 - 2.9)

0.725

ECOG 2

2.90 (0.7 - 11.8)

0.136

3.59 (0.8 - 16.0)

0.094

ECOG 3

2.18 (0.2 - 20.6)

0.498

2.51 (0.3 - 24.3)

0.428

ECOG grouping: (n = 266)

ECOG 0-1

1.00 (Reference)

-

1.00 (Reference)

-

ECOG ≥2

2.64 (0.8 - 8.7)

0.111

3.00 (0.9 - 10.4)

0.083

MRC dyspnea scores (n = 266)

1

1.00 (Reference)

-

1.00 (Reference)

-

2

1.20

0.670

0.66 (0.2 - 2.3)

0.512

3

2.14

0.272

1.01 (0.2 - 6.0)

0.993

4

-

-

-

-

MRC dyspnea score grouping (n = 266)

1

1.00 (Reference)

-

1.00 (Reference)

-

≥2

1.25 (0.6 - 2.7)

0.571

0.81 (0.2 - 2.6)

0.729