Parameter | DcSSc + CVA (n = 6) | DcSSc + no CVA (n = 7) | p value |

Sex | 1 M/5 F (n = 6) | 1 M/6 F (n = 7) | 1 |

Race | 3 AA/3 C (n = 6) | 2 AA/4 C/1 H (n = 7) | N/A |

Age at CVA dx | 60.2 ± 14.9 (n = 5) | N/A | N/A |

Age at SSc dx | 49.2 ± 20.1 (n = 6) | 40.3 ± 9.6 (n = 7) | 0.32 |

Hypertension | 5 yes/1 no (n = 6) | 5 yes/2 no (n = 7) | 1 |

Hyperlipidemia | 3 yes/3 no (n = 6) | 1 yes/6 no (n = 7) | 0.27 |

Prior TIA or CVA | 1 yes/4 no (n = 5) | N/A | N/A |

CAD | 3 yes/3 no (n = 6) | 0 yes/7 no (n = 7) | 0.07 |

Atrial fibrillation | 0 yes/6 no (n = 6) | 0 yes/7 no (n = 7) | 1 |

Diabetes mellitus | 1 yes/5 no (n = 6) | 2 yes/5 no (n = 7) | 1 |

Tobacco use | 3 yes/3 no (n = 6) | 2 yes/5 no (n = 7) | 0.59 |

Family hx of CVA | 1 yes/5 no (n = 6) | 1 yes/6 no (n = 7) | 1 |

Carotid disease | 2 yes/3 no (n = 5) | 0 yes/1 no (n = 1) | 1 |

Anti-nuclear antibody | 4 pos/0 neg (n = 4) | 6 pos/0 neg (n = 6) | 1 |

Scl-70 antibody | 0 pos/2 neg (n = 2) | 3 pos/3 neg (n = 6) | 0.46 |

ACA | 1 pos/2 neg (n =3) | 0 pos/6 neg (n = 6) | 0.33 |

Cr at time of CVA | 1.6 ± 1.0 (n = 4) | N/A | N/A |

Hb at time of CVA | 10.5 ± 2.45 (n = 4) | N/A | N/A |

Alb at time of CVA | 3.7 ± 0.40 (n = 4) | N/A | N/A |