| Variables | 1st evaluation (n = 187) | 2nd evaluation (n = 187) | P |
| HDL (mg/dL) | 58.7 ± 16.1 | 55.2 ± 15.7 | <0.001 |
| Triglycerides (mg/dL) | 127.7± 57.0 | 134.8 ± 59.8 | 0.067 |
| Glucose (mg/dL) | 93.9 ± 20.9 | 97.7 ± 29.1 | 0.042 |
| BMI (kg/m2) | 26.9 ± 5.1 | 27.3 ± 5.2 | 0.069 |
| Waist circumference (cm) | 92.9 ± 13.1 | 92.3 ± 14.1 | 0.252 |
| Systolic Blood Pressure (mmHg) | 139.1 ± 23.5 | 130.6 ± 24.9 | <0.001 |
| Diastolic Blood Pressure (mmHg) | 85.9 ± 12.6 | 82.5 ± 12.0 | <0.001 |
| CRP (mg/dL) | 5.5 (0.16 - 161) | 5.4 (0.75 - 73.9) | 0.069 |
| DAS-28 | 3.87 ± 1.43 | 3.52 ± 1.36 | 0.006 |
| Moderate/high disease activity (>3.2) | 126 (67.4) | 101 (54.0) | 0.006 |
| HAQ | 1.1 (0.5 - 1.6) | 1.1 (0.4 - 1.6) | 0.990 |
| MS (%) | 82 (43.9) | 111 (59.4) | <0.001 |