Parameters | Days | Vehicle Control | SAVA 8A (116 mg/animal) | SAVA 8 B (216 mg/animal) |
Body Weight (g) | Day 0 | 252 ± 2.53 | 242.20 ± 2.16 | 244.50 ± 3.34 |
Day 30 | 334 ± 12.00 | 259.10 ± 7.41*** | 279.70 ± 10.78** | |
SGPT (U/L) | Day 0 | 56.17 ± 10.66 | 55.4 ± 3.68 | 49.8 ± 10.88 |
Day 30 | 58.67 ± 10.59 | 59 ± 3.78 | 53.4 ± 1.922 | |
SGOT (U/L) | Day 0 | 103.7 ± 13.56 | 112.7 ± 5.37 | 106± 1.64 |
Day 30 | 106.21 ± 13.46 | 116.3 ± 5.51 | 109.6 ± 1.70 | |
ALP (IU/L) | Day 0 | 149.3 ± 24.54 | 147.6 ± 2.33 | 130.3 ± 5.51 |
Day 30 | 151.8 ± 24.52 | 151.2 ± 2.25 | 133.9 ± 5.62 | |
Total Bilirubin (mg/dL) | Day 0 | 0.08 ± 0.01 | 0.12 ± 0.00 | 0.10 ± 0.00 |
Day 30 | 0.13 ± 0.01 | 0.15 ± 0.00 | 0.12 ± 0.00 | |
Liver weight (g) | Day 30 | 10.00 ± 0.58 | 8.80 ± 1.40 | 9.60 ± 1.18 |