NCF1 | Neutrophil cytosol factor 1. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). |
NEBL | Nebulette. Binds to actin and plays an important role in the assembly of the Z-disk. May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres (PubMed: 27733623). |
NFATC1 | Isoform 2 might play a role in the assembly of focal adhesion (PubMed: 15004028). |
NPTN | Neuroplastin. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity). |
NUDT22 | Uridine diphosphate glucose pyrophosphatase. Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose. |
NUP153 | Nuclear pore complex protein Nup153. Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. |
NUP58 | Nucleoporin p58/p45. Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. |
OFD1 | Oral-facial-digital syndrome 1 protein. Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. |
OPALIN | Transmembrane protein. |
OR11H1 | Olfactory receptor 11H1 |
OR6N2 | Olfactory receptor 6N2 |
PCDHA8 | Protocadherin alpha-8. Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. |
PDCL3 | Phosducin-like protein 3. Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. |
PEX6 | Peroxisome assembly factor 2. Involved in peroxisome biosynthesis. |
PGM2L1 | Glucose 1,6-bisphosphate synthase. |
PLA2G4C | Cytosolic phospholipase A2 gamma. Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. |
PLCD4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4. Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). |