Gene

Protein Function

ABCA13

ATP-binding cassette sub-family A member 13. ATPase activity, coupled to transmembrane movement of substances. Lipid transport. Neutrophil degranulation.

ABCC1

Multidrug resistance-associated protein 1. Mediates export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency.

ABL1

Tyrosine-protein kinase ABL1. Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis.

ADAMTS9

A disintegrin and metalloproteinase with thrombospondin motifs 9. Cleaves the large aggregating proteoglycans, aggrecan and versican. Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos.

ADIG

Adipogenin. Brown fat cell differentiation. Positive regulation of fat cell differentiation. Spermatogenesis.

AGBL1

Cytosolic carboxypeptidase 4. Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins.

ANKRD20A1

Ankyrin repeat domain-containing protein 20A1.

ANKRD20A3

Ankyrin repeat domain-containing protein 20A3.

ARHGAP21

Rho GTPase-activating protein 21. Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function

ARSD

Arylsulfatase D. Glycosphingolipid metabolism.

BAGE2

B melanoma antigen 2. Candidate gene encoding tumor antigens.

BAGE3

B melanoma antigen 3. Candidate gene encoding tumor antigens.

BBS12

Bardet-Biedl syndrome 12 protein. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed: 20080638).

BCLAF1

Bcl-2-associated transcription factor 1. Death-promoting transcriptional repressor.

BZRAP1

BZRAP1 protein. Benzodiazepine receptor binding.

C4A

Complement C4-A. Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes.