Characteristic

n

Progesterone (ng/ml)

Sickle Cell

Healthy (Control)

% Reduction

Sickle Cell vs. Control

Mean ± SEM

Mean ± SEM

Test Statistics p-value

Age Group (years)

21 - 25

18

48.42 ± 4.83

53.90 ± 11.41

0.652^ns

26 - 30

36

39.38 ± 3.41

56.49 ± 3.64

0.001***

30+

6

37.67 ± 8.36

46.21 ± 10.41

0.515^ns

Trimester

1st Trimester (4 - 12 Wks)

20

20.73 ± 0.88^a

29.04 ± 0.93^a

28.62

<0.0001****

2nd Trimester (13 - 25 Wks)

20

39.24 ± 1.55^b

50.93 ± 2.45^b

22.95

0.0003***

3rd Trimester (26 - 40 Wks)

20

65.80 ± 2.93^c

85.77 ± 2.47^c

23.28

<0.0001****