Metformin + Glitazone

Metformin + Glibenclamide

Metformin

49.5 ± 3.1

47.8 ± 2.5

48.53 ± 1.8

Age (year)

85.87 ± 5.4

85.66 ± 2.6

80.86 ± 4.9

Weight (kg)

32.43 ± 1.5

30.29 ± 0.7

28.87 ± 0.9

BMI (kg/m²)

106.4 ± 3.4

102.66 ± 2.01

101.0 ± 1.3

Waist Circumference (cm)

174.80 ± 9.3

181.07 ± 10.6

158.80 ± 6.2

Total Cholesterol (mg/dl)

191.2 ± 10.2

184.6 ± 9.4

201.07 ± 7.2

Triglyceride (mg/dl)

41.5 ± 2.2

39.53 ± 1.6

39.53 ± 1.6

HDL Cholesterol (mg/dl)

137.6 ± 6.4

131.33 ± 9.9

115.07 ± 6.3

LDL Cholesterol (mg/dl)

140.00 ± 9.07

115.00 ± 6.6

114.00 ± 4.3

FBS (mg/dl)

13.03 ± 2.3

14.7 ± 1.4

14.84 ± 1.4

Fasting Insulin (μU/ml)

3.4 ± 0.1

3.02 ± 0.2

2.69 ± 0.2

Fasting C-peptide (ng/dl)

4.5 ± 0.8

4.3 ± 0.4

4.8 ± 0.4

HOMA Index

0.31 ± 0.01

0.3 ± 0.007

0.3 ± 0.003

QUICKI Index

2.4 ± 0.1

3.5 ± 0.3

4.2 ± 0.7

20/(fasting C-peptide × FPG)