Biochemical Parameters

Normal range

Types of therapy

Naive patients

Monotherapy

Bitherapy

Tritherapy

Creatininemia

Mean (6 - 13 mg/dl)

10.80 ± 1.60^b

12.21 ± 3.82^a

13.50 ± 3.79^a

12.96 ± 2.81^a

Kalemia

Mean (3.6 - 5 mmol/L)

4.44 ± 0.60^a

4.42 ± 0.59^a

4.33 ± 0.68^a

4.32 ± 0.33^a

Natremia

Mean (135 - 145 mmol/L)

143.10 ± 4.06^a

142.77 ± 4.96^a

144.24 ± 4.49^a

143.81 ± 4.17^a

Chloremia

Mean (98 - 105 mmol/L)

100.96 ± 5.27^a

101.11± 3.87^a

102.31 ± 4.15^ab

104.19 ± 3.08^b

Total cholesterolemia

Mean (<2 g/l)

1.40 ± 0.35^b

1.79 ± 0.36^a

1.75 ± 0.34^a

1.64 ± 0.28^a

Cholesterolemia-HDL

Mean (>0.4 g/l)

0.93 ± 0.26^a

0.52 ± 0.18^c

0.53 ± 0.16^c

0.45 ± 0.14^b

Cholesterolemia-LDL

Mean (<1.6 g/l)

0.32 ± 0.14^c

1.31 ± 0.33^a

1.20 ± 0.26^ab

1.14 ± 0.20^b

Triglyceridemia

Mean (<1.5 g/l)

1.04 ± 0.37^a

1.13 ± 0.48^a

1.03 ± 0.49^a

1.16 ± 0.38^a

Glycemia

Mean (0.75 - 1.05 g/l)

0.99 ± 0.19^b

1.07 ± 0.48^a

1.21 ± 0.63^a

0.82 ± 0.16^c

ASAT activity

Mean (10 - 40 UI/ml)

16.06 ± 2.59^b

27.07 ± 10.57^a

27.47 ± 11.37^a

27.81 ± 5.99^a

ALAT activity (UI/mL)

Mean (20 - 60 UI/ml)

18.11± 4.56^a

21.04 ± 12.15^a

20.10 ± 5.03^a

22.62 ± 13.27^a