|
| Sildenafil | Milrinone | SNP | Epoprostenol | Iloprost | Treprostinil |
| Number of PA rings | 12 | 08 | 08 | 08 | 08 | 08 |
| Number of patients | 04 | 02 | 02 | 03 | 03 | 02 |
| Min concentration | 100 pM | 3000 pM | 100 pM | 100 pM | 10 pM | 1 pM |
| Max Concentration | 100 μM | 100 μM | 3 μM | 3 μM | 0.1 μM | 0.3 μM |
| Min log concentration | 1E−10 M | 1E−8.5 | 1E−10 M | 1E−10 M | 1E−11 M | 1E−12 M |
| Max log concentration | 1E−4.0 M | 1E−4.0 M | 1E−5.5 M | 1E−5.5 M | 1E−7 M | 1E−6.5 M |
| Diameter (mm) | 2.79 ± 0.39 | 2.43 ± 0.67 | 2.93 ± 0.62 | 3.5 ± 0.53 | 2.62 ± 0.44 | 3.75 ± 0.26 |
| Emax (gf) | −1.078 | −1.749 | −1.533 | −1.82 | −2.001 | −2.03 |
| Emax (gf/mm) | −0.11 | −0.23 | −0.17 | −0.16 | −0.24 | −0.17 |
| EC50 | 1.06 μM | 1.01 μM | 0.022 μM | 0.029 μM | 0.001 μM | 00003 μM |