Patient | Age - Sex (reference) | Localizations | Clinical presentation and associated pathological conditions | Endoscopy and imaging | Histopathological findings | Treatment | Evolution |
1 | 69 - M (4) | Multiples: cecum, right colon, transverse colon, left colon, stomach, duodenum. | - Rectal bleeding - Immunocompetent patient. No dysimmune or inflammatory or neoplastic associated pathology was found. | Multiple polypoid nodules | - Hyperplastic lymphoid follicles with germinal centers. - Absence of neoplastic cell. Disorganized architecture of the mucosa | Therapeutic abstention | - Persistent nodules without complication. |
2 | 23 - M (5) | Multiples and extents from the rectum to the transverse colon. | - Rectal bleeding - Normal immunity, no giardiasis. | Multiple small nodular formations. | Nodular lymphoid hyperplasia | Therapeutic abstention and endoscopic follow-up | - Not available |
3 | 57 - F (6) | Right colon, cecum, terminal ileum. | - Rectal bleeding, abdominal pain, chronic diarrhea, obstructive symptoms. - History of appendectomy in childhood - High blood pressure |
| - Morphological features compatible with lymphoid lesion. | Laparotomy with right hemicolectomy. | Good evolution after surgery. |
4 | 25 - F (3) | Rectum | - Chronic constipation and rectal bleeding | Nodular area of 3 cm located lower in the rectum, associated with hemorrhoids. | Lymphoid infiltrate in mucosa and submucosa. | Therapeutic abstention | After 2 months: persistent small nodules on sigmoidoscopy. |
5 | 29 - F (3) | Rectum | Incidentally discovered during an antenatal examination. | Polypoid lesion measuring 3 cm in greatest dimension. | Lymphoid infiltrate in mucosa and submucosa. | Endoscopic resection | Good evolution, normal rectoscopy 3 years after resection of the lesion. |
6 | 29 - M (3) | Rectum | Rectal bleeding evolving for 6 months | Nodular rectal mucosa extending over 3 to 4 cm, associated with hemorrhoids. | Lymphoid infiltrate in mucosa and submucosa. | Not available | Absence of complication after 5 years of evolution. |
7 | 55 - M (3) | Rectum | Rectal bleeding | - Colonoscopy: four nodules of 2 to 3 mm in greatest dimension. - Barium enema: Absence of other localizations. | Lymphoid infiltrate in mucosa and submucosa. | Excisional biopsy of the 4 nodules | - Recurrence of the nodules respectively at 4 months and 4 years after their excision. - Good evolution, one year after the last excision. |
8 | 37 - F (3) | Rectum | Incidentally discovered | Polypoid lesion of 3 × 1 cm. | Lymphoid infiltrate in mucosa and submucosa. | Excisional biopsy | Good evolution 20 years after excisional biopsy. |
9 | 30 - F (3) | Rectum | Incidentally discovered | Polypoid lesion of 2 × 1 cm. | Lymphoid infiltrate in mucosa and submucosa. | Excisional biopsy | Absence of follow-up |
10 | 58 - F (present case) | Right colic angle | - Abdominal pain, chronic constipation and rectal bleeding after Covid 19 infection. - History of appendectomy in childhood. | - Colonoscopy: presence of a bulging, non-ulcerated mass, measuring 3.5 cm in greatest dimension, located at the right colic angle. - Thoraco-abdomino-pelvic computed tomography: right colonic wall thickening and enhanced nodule formation. | -Presence of numerous hyperplastic lymphoid follicles in mucosa and submucosa. -Identical morphology within the remaining colonic and ileal walls with a variable amount of lymphoid follicles of varying sizes. | Laparotomy with right hemicolectomy. | Absence of recurrence or complication 6 months after surgery. |