Struma ovarii

Present case


-A mature teratoma composed either exclusively or predominantly of thyroid tissue

-Only thyroid tissue is present in the lt. ovarian tumor


-The most common type of monodermal teratoma


-Reproductive years

(mainly 40 - 60 years old)

-34 years old

Clinical manifestations

-Usually present with pain and/or a pelvic mass

-Ascites (up to 1/3 of patients)

-Rarely hyperthyroidism

-Secondary infertility

-Polycystic ovary syndrome (rt ovary)

-No ascites and hyperthyroidism

Macroscopic findings (Tumor size)

-Usually unilateral and solid

(<10 cm)

-Lt. ovary occupied by cystic and solid tumor tissues (7 cm)

Serum CA125 level

-High level of CA125 is suggestive of malignancy

-Within normal limits

(7.2 U/ml)


-Mature thyroid tissue is present predominantly (over 50%) in mature ovarian teratoma

-Thyroid tissue is present exclusively in lt. ovarian cystic tumor with papillary projection

Malignant transformation

-About 5%

-Mostly papillary carcinoma with BRAF mutations and RET/PTC rearrangements


Prognosis & follow-up time

-Most cases of typical struma ovarii are benign.

-The outcome of histologically and biologically malignant thyroid type tumors in struma is favourable

-Well, 7 months after the operation