| Struma ovarii | Present case | |
| Definition | -A mature teratoma composed either exclusively or predominantly of thyroid tissue | -Only thyroid tissue is present in the lt. ovarian tumor |
| Epidemiology | -The most common type of monodermal teratoma | |
| Age | -Reproductive years (mainly 40 - 60 years old) | -34 years old |
| Clinical manifestations | -Usually present with pain and/or a pelvic mass -Ascites (up to 1/3 of patients) -Rarely hyperthyroidism | -Secondary infertility -Polycystic ovary syndrome (rt ovary) -No ascites and hyperthyroidism |
| Macroscopic findings (Tumor size) | -Usually unilateral and solid (<10 cm) | -Lt. ovary occupied by cystic and solid tumor tissues (7 cm) |
| Serum CA125 level | -High level of CA125 is suggestive of malignancy | -Within normal limits (7.2 U/ml) |
| Histopathology | -Mature thyroid tissue is present predominantly (over 50%) in mature ovarian teratoma | -Thyroid tissue is present exclusively in lt. ovarian cystic tumor with papillary projection |
| Malignant transformation | -About 5% -Mostly papillary carcinoma with BRAF mutations and RET/PTC rearrangements | -None |
| Prognosis & follow-up time | -Most cases of typical struma ovarii are benign. -The outcome of histologically and biologically malignant thyroid type tumors in struma is favourable | -Well, 7 months after the operation |