Study	SVD	NSVD	BVF	Endocarditis	Inclusion	Exclusion
Makkar et al. 2020	Any change in valve function (a decrease of one NYHA functional class or more) resulting from an intrinsic abnormality of the valve that causes stenosis or regurgitation	Not Defined	Not Defined	Abscess, paravalvular leak, pus, or vegetation confirmed during a re-operation or autopsy	Severe AS, NYHA class II or greater, intermediate surgical risk	Inoperability, acute MI within 30 days, bicuspid aortic valve, LVEF < 20%, severe renal insufficiency, life expectancy < 2 years
Tzamalis et al. 2020	EAPCI/ESC/EACTS definitions	EAPCI/ESC/EACTS definitions	EAPCI/ESC/EACTS definitions	Not defined	Severe AS with intermediate or low surgical risk	Surgical patients who required concomitant mitral repair, mitral replacement, or CABG
Sondergaard et al 2019	EAPCI/ESC/EACTS definitions	EAPCI/ESC/EACTS definitions	EAPCI/ESC/EACTS definitions	Modified Duke Criteria	≥70 years of age with severe AS, NYHA class II or greater, regardless with low surgical risk	another severe heart valve disease or CAD requiring intervention, previous cardiac surgery, MI or stroke within 30 days, severe renal failure requiring dialysis, or pulmonary failure
Gleason et al. 2018	EAPCI/ESC/EACTS definitions	EAPCI/ESC/EACTS definitions	EAPCI/ESC/EACTS definitions	Not defined	Severe AS, NYHA class II or greater at high surgical risk	Recent MI within 30 days, CVA within 6 months, live expectancy < 12 months
Mack et al. 2015	Not defined	Not defined	Not defined	Not defined	Severe AS with high surgical risk	Bicuspid aortic valve, CAD requiring revascularization, LVEF < 20%, severe MR or AR, severe renal insufficiency, or a recent neurologic event.