III

28 (77.8)

23 (63.9)

0.34

IV

8 (22.2)

11 (30.6)

0.34

Blood pressure baseline

Systolic mmHg

124 ± 25.8

120 ± 19.9

0.42

Diastolic mmHg

70 ± 12.5

74 ± 9.7

0.12

Systolic function, % ejection fraction

Preserved, 40% - 49%

13 (36.1)

12 (33.3)

0.80

Reduced, 30% - 39%

16 (44.4)

21 (58.3)

0.36

Reduced, <30%

7 (19.4)

3 (8.3)

0.17

Creatinine > 130 mmol/L

12 (33.3)

12 (33.3)

1.00

Glomerular filtration rate < 60 mL/min

25 (69.4)

22 (61.1)

0.46

Anemia < 120 g/L

19 (52.7)

15 (41.7)

0.29

Dyspnea

None

1 (2.8)

2 (5.6)

0.56

Mild

8 (22.2)

6 (16.6)

0.55

Moderate

23 (63.9)

22 (61.1)

0.81

Severe

4 (11.1)

6 (16.7)

0.50

Fatigue

None/missing

3 (8.3)

4 (11.1)

0.69

Mild

10 (27.8)

7 (19.4)

0.41

Moderate

16 (44.4)

15 (41.7)

0.81

Severe

7 (19.4)

10 (27.8)

0.41

Treatment

Renin-angiotensin system blockade

32 (86.1)

33 (91.7)

0.69

Beta-blocker

30 (83.3)

31 (86.1)

0.74

Mineralocorticoid receptor antagonist

10 (27.8)

13 (36.1)

0.45

Loop diuretics

32 (88.9)

30 (83.3)

0.50

Digitalis

8 (22.2)

5 (13.9)

0.36

Nitrates

12 (33.3)

11 (30.6)

0.80

Statins

12 (33.3)

18 (50.0)

0.15

Anticoagulants

17 (47.2)

17 (47.2)

1.00

Acetylsalicylic acid/platelet inhibitors

21 (58.3)

15 (41.7)

0.16

Number of other drug treatments, median

5

6

0.73

Devices, procedures

Cardiac resynchronisation therapy

3 (8.3)

4 (10.1)

0.35

Pacemaker

4 (11.1)

5 (13.9)

0.72

Valve operations

4 (11.1)

3 (8.3)

0.69

History of coronary artery bypass graft/percutaneous coronary intervention

17 (47.2)

13 (36.1)

0.34