III | 28 (77.8) | 23 (63.9) | 0.34 |
IV | 8 (22.2) | 11 (30.6) | 0.34 |
Blood pressure baseline |
|
|
|
Systolic mmHg | 124 ± 25.8 | 120 ± 19.9 | 0.42 |
Diastolic mmHg | 70 ± 12.5 | 74 ± 9.7 | 0.12 |
Systolic function, % ejection fraction |
|
|
|
Preserved, 40% - 49% | 13 (36.1) | 12 (33.3) | 0.80 |
Reduced, 30% - 39% | 16 (44.4) | 21 (58.3) | 0.36 |
Reduced, <30% | 7 (19.4) | 3 (8.3) | 0.17 |
Creatinine > 130 mmol/L | 12 (33.3) | 12 (33.3) | 1.00 |
Glomerular filtration rate < 60 mL/min | 25 (69.4) | 22 (61.1) | 0.46 |
Anemia < 120 g/L | 19 (52.7) | 15 (41.7) | 0.29 |
Dyspnea |
|
|
|
None | 1 (2.8) | 2 (5.6) | 0.56 |
Mild | 8 (22.2) | 6 (16.6) | 0.55 |
Moderate | 23 (63.9) | 22 (61.1) | 0.81 |
Severe | 4 (11.1) | 6 (16.7) | 0.50 |
Fatigue |
|
|
|
None/missing | 3 (8.3) | 4 (11.1) | 0.69 |
Mild | 10 (27.8) | 7 (19.4) | 0.41 |
Moderate | 16 (44.4) | 15 (41.7) | 0.81 |
Severe | 7 (19.4) | 10 (27.8) | 0.41 |
Treatment |
|
|
|
Renin-angiotensin system blockade | 32 (86.1) | 33 (91.7) | 0.69 |
Beta-blocker | 30 (83.3) | 31 (86.1) | 0.74 |
Mineralocorticoid receptor antagonist | 10 (27.8) | 13 (36.1) | 0.45 |
Loop diuretics | 32 (88.9) | 30 (83.3) | 0.50 |
Digitalis | 8 (22.2) | 5 (13.9) | 0.36 |
Nitrates | 12 (33.3) | 11 (30.6) | 0.80 |
Statins | 12 (33.3) | 18 (50.0) | 0.15 |
Anticoagulants | 17 (47.2) | 17 (47.2) | 1.00 |
Acetylsalicylic acid/platelet inhibitors | 21 (58.3) | 15 (41.7) | 0.16 |
Number of other drug treatments, median | 5 | 6 | 0.73 |
Devices, procedures |
|
|
|
Cardiac resynchronisation therapy | 3 (8.3) | 4 (10.1) | 0.35 |
Pacemaker | 4 (11.1) | 5 (13.9) | 0.72 |
Valve operations | 4 (11.1) | 3 (8.3) | 0.69 |
History of coronary artery bypass graft/percutaneous coronary intervention | 17 (47.2) | 13 (36.1) | 0.34 |