Variable

Control group (n)31

Nicorandil group (n)31

p value

Post-op uses of inotropic drugs

yes

18 (59%)

9 (29%)

0.018*

No

13 (41%)

22 (71%)

Overall number of inotropic drugs

1.48 ± 1.07

0.66 ± 0.73

0.048*

Post-operative R-wave amplitude reduction in V5 (4 h) mm

4.6 ± 0.85

3.63 ± 0.89

0.011*

post-op LVEF%

56.48 ± 3.66

62.22 ± 3.55

0.048*

Post-operative CKMB

4 hours

51.76 ± 3.87

38.67 ± 3.44

0.031*

12 hours

43.08 ± 2.43

34.75 ± 2.33

0.001*

48 hours

14.05 ± 2.66

13.05 ± 3.55

0.816

Post-operative Troponin I

4 hours

1.36 ± 0.18

1.12 ± 0.16

0.017*

12 hours

1.54 ± 0.31

1.18 ± 0.22

0.006*

48 hours

0.54 ± 0.44

0.52 ± 0.45

0.741

Post-operative

tumor necrosis factor alpha (TNF-α)

4 hours

20.3 ± 2.44

15.17 ± 1.56

0.001*

12 hours

16.36 ± 2.37

13.17 ± 1.55

0.081*

48 hours

12.33 ± 1.44

12.1 ± 1.25

0.649

Post-operative

interleukin 6 (IL-6)

4 hours

36.71 ± 2.99

27.06 ± 3.4

0.021*

12 hours

29.84 ± 5.66

23.18 ± 3.46

0.004*

48 hours

22.66 ± 1.99

21.77 ± 2.36

0.162

Intensive care unit stay

2.66 ± 0.55

2.49 ± 0.33

0.588

Length of post-operative hospital stay

11.10 ± 1.35

10.85 ± 1.20

0.964