Characteristics

All (183)

without a history

of HCC (166) a

with a history of HCC (17) b

p

a vs. b

Age (year)*

68 (18 - 91)

65 (18 - 91)

71 (49 - 84)

<0.001

Male: Female

89:94

75:91

14:3

<0.001

BMI (kg/m²)

22.6 (14.4 - 37.4)

22.7 (14.4 - 37.4)

22.0 (18.6 - 34.9)

NS

DCV/ASV:SOF/LDV: SOF/RBV:OBV/PTV/rit: EBR/GZR:PIB/GLE

39:55:42:6:9:32

32:52:38:5:8:30

7:3:4:0:1:2

NS

Duration of the follow-up (months)*

33.4 (12 - 58.2)

32.8 (12 - 58.2)

40.7 (12 - 57.0)

NS

Previous IFN treatment, Non-responder: Relapse

15:38

15:6

0:2

NS

DM

8

5

3

NS

Daily alcohol intake ≥ 40 g/day

2

1

1

NS

HCV genotype 1:2:3

123:58:2

85:53:2

12:5:0

NS

HCV RNA (Log IU/ml)*

6.2 (2.3 - 7.4)

6.2 (2.3 - 7.4)

5.8 (4.5 - 7.3)

NS

White cell count (/μl)*

5000 (2100 - 18,000)

5000 (360 - 10,600)

4400 (2600 - 18,000)

NS

Hemoglobin (g/dl)*

13.5 (7.3 - 17.2)

13.5 (7.3 - 17.2)

13.1 (11.0 - 15.4)

NS

Platelets (10⁴/μl)*

17.0 (5.2 - 80.9)

17.3 (5.2 - 68.0)

11.7 (8.3 - 80.9)

NS

Aspartate aminotransferase (IU/L)*

41 (4 - 361)

39 (4 - 361)

50 (27 - 213)

NS

Alanine aminotransferase (IU/L)*

40 (7 - 472)

39 (7 - 472)

51 (21 - 212)

NS

Total bilirubin (mg/dl)*

0.73 (0.34 - 5.00)

0.73 (0.34 - 5.00)

0.71 (0.5 - 1.84)

NS

Albumin (g/dl)*

4.1 (2.2 - 5.2)

4.1 (2.4 - 5.2)

3.7 (2.6 - 4.6)

NS

Creatinine (mg/dl)*

0.72 (0.45 - 8.69)

0.70 (0.45 - 8.69)

0.82 (0.56 - 1.30)

NS

Alpha-fetoprotein (AFP) (ng/ml)*

Before

5.0 (1 - 560)

4.0 (1 - 450)

9.0 (1 - 560)

<0.001

SVR24

4.0 (1 - 133)

3.0 (1.0 - 19)

6.0 (10 - 133)

<0.001

Fib-4*

2.82 (0.09 - 5.72)

2.52 (0.16 - 3.99)

4.35 (1.52 - 5.06)

<0.001

LS0 (kPa)*

8.0 (2.5 - 40.9)

7.5 (2.5 - 40.9)

16.1 (7.3 - 28.0)

<0.05

LS24 (kPa)*

6.0 (2.6 - 31.6)

5.8 (2.6 - 31.6)

14.8 (9.9 - 29.1)

<0.01

LS48 (kPa)*

5.3 (2.4 - 29.5)

5.0 (2.4 - 25.1)

12.0 (5.3 - 29.5)

<0.001

HCC

Occurrence 7

Recurrence 9