variable

SE

HR

95.0% CI

P

Gender (male vs female)

0.220

1.075

0.699 - 1.653

0.742

Age (≤60 vs >60)

0.010

1.005

0.985 - 1.025

0.639

Tumor site (head vs body and tail)

0.273

0.650

0.381 - 1.109

0.114

Differentiation (well, moderate and poor)

0.199

1.482

1.002 - 2.191

0.049

T stage (1, 2, 3)

0.170

1.035

0.742 - 1.443

0.838

TNM stage (I, II, III)

0.162

1.561

1.137 - 2.144

0.006

Perinerual invasion (present vs absent)

0.307

2.14

1.172 - 3.908

0.013

Vascular invasion (present vs absent)

0.357

1.425

0.708 - 2.867

0.321

LN metastasis (present vs absent)

0.221

2.106

1.365 - 3.251

0.001

Tumor SPARC (positive vs negative)

0.246

0.758

0.469 - 1.227

0.260

Stroma SPARC (positive vs negative)

0.245

2.151

1.330 - 3.477

0.002