| Cases | |||
| Clinicopathologic factors | Lymph node metastasis (n = 96) | Non-lymph node metastasis (n = 90) | p value |
| Gender |
|
| 0.355 |
| Male | 74 | 65 |
|
| Female | 22 | 25 |
|
| Age |
|
| 0.388 |
| ≤60 | 52 | 56 |
|
| >60 | 44 | 34 |
|
| Tumor location |
|
| 0.412 |
| Upper stomach 1/3 | 25 | 17 |
|
| Middle stomach 1/3 | 16 | 17 |
|
| Lower stomach 1/3 | 55 | 56 |
|
| Gross type |
|
| 0.233 |
| Borrmann I | 6 | 8 |
|
| Borrmann II | 26 | 32 |
|
| Borrmann III | 57 | 41 |
|
| Borrmann IV | 7 | 9 |
|
| Tumor size |
|
| 0.288 |
| ≤4 cm | 59 | 63 |
|
| >4 cm | 37 | 27 |
|
| Tumor depth |
|
| 0.001 |
| pT1 | 7 | 34 |
|
| pT2 | 21 | 27 |
|
| pT3 - 4 | 68 | 29 |
|
| Differentiation degree |
|
| 0.155 |
| High | 4 | 13 |
|
| Medium | 30 | 26 |
|
| Low | 62 | 51 |
|
| Clinical stage |
|
| 0.0001 |
| I | 7 | 45 |
|
| II | 17 | 25 |
|
| III | 52 | 17 |
|
| IV | 20 | 3 |
|
| Expression of VEGF-C |
|
| 0.001 |
| Positive | 71 | 31 |
|
| Negative | 25 | 59 |
|
| Expression of VEGFR-3 |
|
| 0.001 |
| Positive | 43 | 19 |
|
| Negative | 53 | 71 |
|