S. No.

Compound No.

Cell line

Ascorbate concentration (mM)

Incubation time of cells with ascorbate (h)

IC₅₀ nM (Nanomolar),

pM (Pico molar)

1.

2

KB (FR⁺)

3

16

14.7 nM

2.

2

KB (FR⁺)

5

16

12.6 nM

3.

3

KB (FR⁺)

3

2

Non-toxic

4.

3

KB (FR⁺)

5

2

Non-toxic

5.

3

KB (FR⁺)

0

12

Non-toxic

6.

3

KB (FR⁺)

3

12

0.14 pM

7.

3

KB (FR⁺)

5

12

0.0011 pM

8.

4

KB (FR⁺)

3

68

Non-toxic

9.

4

KB (FR⁺)

5

68

Non-toxic

10

3

A549 (FR⁻)

3

12

Non-toxic

11.

3

A549 (FR⁻)

5

12

Non-toxic