Mean ± S.D. (Percent edema inhibition)

Analgesic activity

Comp.

No.

1 h

2 h

3 h

4 h

5 h

6 h

Potency

No. of writhing movements

Percent inhibition

Potency

17a

0.05 ± 0.04

(76.40)

0.08 ± 0.01

(68.42)

0.18 ± 0.003

(66.41)

0.22 ± 0.02

(52)

0.14 ± 0.06

(49.42)

0.12 ± 0.06

(40.71)

0.46

10

81.81

0.97

17b

0.21 ± 0.05

(88.87)

0.21 ± 0.02

(71.31)

0.12 ± 0.04^a

(62.74)

0.13 ± 0.04

(58.04)

0.19 ± 0.04

(50.10)

0.18 ± 0.04

(55.37)

0.62

8

85.45

1.02

18a

0.21 ± 0.03

(45.32)

0.09 ± 0.003^a

(47.48)

0.25 ± 0.03

(51.21)

0.17 ± 0.05

(53.42)

0.48 ± 0.07

(57.39)

0.12 ± 0.06^a

(85)

0.96

19

65.45

0.78

18b

0.25 ± 0.04

(55)

0.32 ± 0.01

(56)

0.32 ± 0.01

(61.36)

0.10 ± 0.01

(50.21)

0.45 ± 0.09

(72.35)

0.43 ± 0.02

(87.21)

0.98

14

74.54

0.89

19a

0.27 ± 0.05

(17.40)

0.33 ± 0.04

(23.64)

0.45 ± 0.08

(59.41)

0.45 ± 0.05

(64)

0.45 ± 0.07

(70.26)

0.25 ± 0.04

(90.63)

1.02

12

78.81

0.94

19b

0.15 ± 0.06

(20.51)

0.23 ± 0.07

(31.36)

0.21 ± 0.02

(46.07)

0.39 ± 0.05

(57.42)

0.23 ± 0.07

(73)

0.24 ± 0.04^a,b

(90.88)

1.02

10

81.81

0.97

20a

0.24 ± 0.02

(4.21)

0.23 ± 0.03

(11.32)

0.25 ± 0.03

(30.22)

0.25 ± 0.04

(47)

0.26 ± 0.02

(59.41)

0.47 ± 0.07

(55.61)

0.63

27

50.90

0.60

20b

0.23 ± 0.04

(6.26)

0.23 ± 0.01

(14.21)

0.47 ± 0.06

(34.52)

0.22 ± 0.022

(44.39)

0.23 ± 0.03

(57.23)

0.47 ± 0.1

(63)

0.71

21

61.81

0.73

21a

0.23 ± 0.02

(11.65)

0.31 ± 0.04

(21.64)

0.33 ± 0.03

(33.61)

0.22 ± 0.03^a,b

(59)

0.36 ± 0.05

(68.32)

0.14 ± 0.03^a,b

(89)

1

25

54.54

0.65

21b

0.23 ± 0.05

(8.70)

0.29 ± 0.05

(26.87)

0.25 ± 0.05

(34.38)

0.25 ± 0.03^a,b

(62.43)

0.24 ± 0.05^a,b

(61.90)

0.18 ± 0.01

(91.70)

1.03

23

58.18

0.69

22a

0.17 ± 0.04

(0)

0.45 ± 0.02

(11.50)

0.24 ± 0.02

(22.84)

0.37 ± 0.05

(33.44)

0.19 ± 0.03^a,b

(42.31)

0.23 ± 0.08^a

(48.21)

0.54

55

---

---

22b

0.24 ± 0.02

(2.40)

0.25 ± 0.02

(8.43)

0.13 ± 0.02

(23.36)

0.21 ± 0.03

(38.36)

0.50 ± 0.04

(46.53)

0.12 ± 0.05

(49.57)

0.56

57

---

---

23a

0.23 ± 0.03

(12.04)

0.23 ± 0.06

(21.23)

0.37 ± 0.02

(44.20)

0.37 ± 0.05

(52.27)

0.23 ± 0.03

(72.21)

0.37 ± 0.03

(89.93)

1.01

12

78.81

0.94

23b

0.36 ± 0.04

(14.15)

0.43 ± 0.04

(27.31)

0.35 ± 0.03

(50)

0.21 ± 0.02

(63.25)

0.22 ± 0.06

(74.30)

0.42 ± 0.02

(92.56)

1.04

10

81.81

0.97