Mean ± S.D. (Percent edema inhibition)

Analgesic activity

Comp.

No.

1 h

2 h

3 h

4 h

5 h

6 h

Potency

No. of writhing movements

Percent inhibition

Potency

13a

0.22 ± 0.06

(17.9)

0.23 ± 0.01

(0)

0.53 ± 0.08

(51.37)

0.21 ± 0.05

(41.32)

0.54 ± 0.04

(53.67)

0.37 ± 0.03

(61.40)

0.69

27

50.90

0.60

13b

0.19 ± 0.02

(12.4)

0.21 ± 0.05

(8.61)

0.47 ± 0.08

(39.55)

0.46 ± 0.05

(52.47)

0.18 ± 0.03

(62.43)

0.24 ± 0.02

(89)

1

25

54.54

0.65

14a

0.27 ± 0.02

(0)

0.18 ± 0.04

(0)

0.34 ± 0.01

(19.32)

0.36 ± 0.01

(27.74)

0.24 ± 0.06

(33.27)

0.21 ± 0.02

(42.85)

0.48

57

---

---

14b

0.36 ± 0.07

(3.69)

0.22 ± 0.03

(10.2)

0.35 ± 0.05

(17.86)

0.41 ± 0.07

(38.31)

0.21 ± 0.03

(41.84)

0.61 ± 0.04

(61.90)

0.69

43

21.81

0.26

15a

0.22 ± 0.07

(3.40)

0.17 ± 0.03

(7.39)

0.46 ± 0.03

(21.74)

0.34 ± 0.04

(11.15)

0.23 ± 0.02

(42.58)

0.22 ± 0.04

(55.80)

0.63

33

40

0.47

15b

0.22 ± 0.02

(7.39)

0.48 ± 0.08

(18.2)

0.35 ± 0.02

(34.58)

0.24 ± 0.02^a,b

(45.63)

0.35 ± 0.05

(51.43)

0.43 ± 0.01

(69.20)

0.78

29

47.27

0.56

16a

0.37 ± 0.03

(0)

0.31 ± 0.01

(13.4)

0.38 ± 0.02

(31.23)

0.24 ± 0.05

(43.51)

0.29 ± 0.02

(52.10)

0.36 ± 0.05

(66)

0.74

27

50.90

0.60

16b

0.46 ± 0.08

(11.5)

0.24 ± 0.03^a,b

(17.3)

0.35 ± 0.08

(41.30)

0.33 ± 0.04

(48.37)

0.24 ± 0.01^a,b

(61)

0.28 ± 0.03^a

(84)

0.94

23

58.18

0.69