Mean ± S.D. (Percent edema inhibition)

Analgesic activity

Comp.

No.

1 h

2 h

3 h

4 h

5 h

6 h

Potency

No. of writhing movements

Percent inhibition

Potency

9a

0.21 ± 0.03

(9.50)

0.25 ± 0.04

(5.17)

0.18 ± 0.02^a

(13.03)

0.43 ± 0.02

(28.67)

0.28 ± 0.08

(43.39)

0.21 ± 0.02^a

(60.66)

0.68

37

32.72

0.39

9b

0.22 ± 0.02

(2.17)

0.14 ± 0.05

(3.07)

0.48 ± 0.07

(11.4)

0.45 ± 0.09

(27.85)

0.12 ± 0.04

(31.59)

0.54 ± 0.08

(69.52)

0.78

27

50.90

0.60

9c

0.15 ± 0.06

(10.3)

0.44 ± 0.01

(16.5)

0.18 ± 0.04

(36.5)

0.34 ± 0.02

(43.41)

0.17 ± 0.03^a,b

(73.52)

0.46 ± 0.09

(89.10)

1

25

54.54

0.65

9d

0.19 ± 0.04

(15.9)

0.31 ± 0.02

(19.7)

0.42 ± 0.09

(32.8)

0.36 ± 0.02

(52.36)

0.25 ± 0.01^a,b

(78.65)

0.21 ± 0.04

(89.72)

1.01

23

58.18

0.69

10a

0.27 ± 0.02

(6.08)

0.43 ± 0.06

(22.5)

0.45 ± 0.05

(31.52)

0.23 ± 0.08

(41.37)

0.36 ± 0.05

(41.49)

0.22 ± 0.02

(59.43)

0.67

14

74.54

0.89

10b

0.19 ± 0.06

(17.3)

0.14 ± 0.03

(20.9)

0.37 ± 0.01

(31.73)

0.41 ± 0.07

(39.24)

0.23 ± 0.06

(43.26)

0.23 ± 0.08

(61.42)

0.69

12

78.81

0.94

10c

0.44 ± 0.08

(0.00)

0.23 ± 0.05

(16.4)

0.36 ± 0.05

(41.28)

0.21 ± 0.02

(48.31)

0.34 ± 0.02

(66.82)

0.22 ± 0.04

(80.42)

0.90

9

83.63

1

10d

0.41 ± 0.03

(4.18)

0.32 ± 0.01

(27.2)

0.12 ± 0.02

(39.31)

0.21 ± 0.06

(52.45)

0.45 ± 0.05

(71.34)

0.45 ± 0.05

(89.83)

1.01

7

87.27

1.04

11a

0.42 ± 0.01

(3.48)

0.24 ± 0.02

(8.31)

0.41 ± 0.01

(23.21)

0.33 ± 0.03

(45.32)

0.24 ± 0.02

(69.45)

0.21 ± 0.04

(88.40)

0.97

24

56.36

0.67

11b

0.16 ± 0.04

(7.32)

0.42 ± 0.04

(11.4)

0.48 ± 0.08

(22.91)

0.21 ± 0.05

(35.37)

0.22 ± 0.06

(63.49)

0.36 ± 0.05

(88.67)

0.99

23

58.18

0.69

12a

0.49 ± 0.003

(21.0)

0.32 ± 0.04

(33.6)

0.25 ± 0.06

(49.56)

0.34 ± 0.03

(61.52)

0.25 ± 0.11

(81.63)

0.12 ± 0.09^a

(91.89)

1.03

16

70.90

0.84

12b

0.19 ± 0.03

(17.4)

0.34 ± 0.03

(26.8)

0.44 ± 0.08

(58.32)

0.25 ± 0.04

(71.43)

0.09 ± 0.06

(83.51)

0.15 ± 0.12^a

(92.04)

1.04

13

76.36

0.91