Symbol

Definition(Unit)

Value

Ref

y

Tumor volume (vol)

-

-

Q

Cell nutrient density (mol/vol)

-

-

q

Minimum cell nutrient density (mol/vol)

0.0021 - 0.0099

assume

${\mu }_m$

Maximum growth rate (per day)

0.41 - 1.58

[18]

d

Death rate (per day)

0.28 - 1.43

[18]

${\alpha }_1$

Nutrient uptake coefficient (mol/(vol day))

0.0084 - 0.70

assume

$p_1$

Reduction in nutrient uptake rate (-)

0.17 - 0.47

assume

$\tau$

Time delay (day)

10

[1]

$\overline{y}$

Tumor size 10 days before treatment (vol)

375

[22]