Factors | H-bond donor | Hydrophobic/ non-polar | Negative ionic | Positive ionic | Electron- withdrawing | Other |
1 | 0.051 | 0.573 | 0.005 | 0.050 | 0.190 | 0.132 |
2 | 0.058 | 0.574 | 0.005 | 0.054 | 0.188 | 0.122 |
3 | 0.063 | 0.571 | 0.004 | 0.058 | 0.190 | 0.115 |
4 | 0.064 | 0.561 | 0.003 | 0.057 | 0.194 | 0.121 |
5 | 0.065 | 0.556 | 0.002 | 0.057 | 0.196 | 0.123 |