Parameters

Group I

Control group

Mean ± SD

Group II

CONPs

group

Mean ± SD

Group III

Oxaliplatin-treated

group

Mean ± SD

Group IV

Oxaliplatin & CONPs group

Mean ± SD

Area percentage of collagen fibers

1.19 ± 0.03

1.8 ± 0.08

10.12 ± 3.1**

3.4 ± 0.5^#

Area percentage of caspase 3 immunoexpression

41.2 ± 0.9

41.8 ± 0.7

69.8 ± 2.8***

42.3 ± 0.005^#

PCNA-Labeling Index (PCNA-LI)

29.2 ± 8.8

28.8 ± 8.2

22.5 ± 5.6*

24.8 ± 7.9#