Title of the screened study

Objective of the study

Characteristics of the study

Findings of the study

Reference

“A randomized controlled trial found that high-intensity interval training improved serum brain-derived neurotrophic factors among stroke patients”

The outcomes of HIIT (high-intensity interval cardio training) and MICT (moderate-intensity continuous training) upon stroke patients’ cerebral oxygenation, peak cardiac output (CO), & serum brain-derived neurotrophic factor were studied.

Sample size = 23

Age limit = 55 years

Study type = randomized controlled trial

In stroke patients, HIIT enhanced aerobic capacity by increasing the amount of oxygen extracted from the systemic tissue. After HIIT, there was an increase in the amount of oxygen that the brain used in the hemisphere that had been engaged.

(Hsu et al., 2021)

“Atherosclerotic arterial stiffness and High-Intensity Interval Training and 24 h blood pressure responses: A systematic review and meta-analysis”

HIIT and MICT will be compared with regard to central arterial stiffness & 24 hour blood pressure results.

Study type = Meta-analysis

Pulse arterial stiffness, as well as wave index, were used to measure central arterial stiffness following both high-intensity interval training & moderate- intensity continuous training and/or 24 hour blood pressure outcome measurements.

When compared to MICT, HIIT results in a greater drop in diastolic blood pressure during the night. In addition, it was discovered that HIIT led to a drop in daytime blood pressure that was almost significantly bigger than that of MICT.

(Way et al., 2019)

“Exercise Reroutes to Kynurenine Pathway & Diminishes Plasma Neurofilament Chain with Multiple Sclerosis”

The goal of this research was to evaluate the acute and training effects of high-intensity interval training as well as conventional physical rehabilitation affecting plasma neurofilament light chain & kynurenine pathway of tryptophan degeneration metabolites in patients.

Study type= Randomized trail

A total of 69 people living with MS with scores between 3.0 and 6.0 on the Expanded Disability Status Scale were randomly allocated to either the HIIT or MCT group.

Acute exercise resulted in a decrease in pNfL and an increase in the flux through the KYN pathway, which leads to the production of neuroprotective kynurenic acid (KA).

Changes in pNfL were found to have a positive correlation with changes in KA and a negative correlation with the ratio of quinolinic acid to KA.

(Joisten et al., 2021)

“Effects of Endurance Exercise Modalities on Arterial Stiffness in Patients Randomized Controlled Trial for Patients With Unipolar Depression”

To explore the impact of different types of exercise on the severity index of depression and arterial stiffness in patients who suffer from unipolar depression.

Sample size = 34

Study type = Randomized trail

Both training regimens were found to have significant impacts on the lowering of symptoms of depression. While high intensity interval training was more successful in reducing the degree of depression, Additional decreases in peripheral arterial stiffness were seen after metabolic conditioning exercise.

(Hanssen et al., 2018)