| Advantages | Disadvantage |
Sodium hypochlorite | °wide-spectrum antibacterial action on spores, yeasts and viruses | °cytotoxicity proportional to its concentration 2.5% is the best concentration |
EDTA | °removal of smear layer and mineral debris | °no action on organic debris decreased action on contact with sodium hypochlorite |
Chlorhexidine | local antiseptic chemical safety broad-spectrum bactericide, antifungal | °reduced action on organic debris |