Baseline

12 months

p-value

Change

Rate of change (%)

PPD (mm)

EMD + DBBM + CM

8.00 ± 0.53

3.67± 0.33

0.007^$

4.33 ± 0.29

54.38 ± 1.89

EMD + DBBM

8.11 ± 0.48

4.78 ± 0.32

0.007^$

3.33 ± 0.47

40.23 ± 4.18

p-value

0.931

0.015^$

0.098

0.021^$

CAL (mm)

EMD + DBBM + CM

9.22 ± 0.62

4.89 ± 0.46

0.007^$

4.33 ± 0.33

47.43 ± 2.72

EMD + DBBM

8.67 ± 0.47

5.33 ± 1.58

0.007^$

3.33 ± 029

39.15 ± 3.85

p-value

0.401

0.551

0.071

0.11

GR (mm)

EMD + DBBM + CM

1.22 ± 0.52

1.22 ± 0.49

1

0.00 ± 0.24

ND

EMD + DBBM

0.56 ± 0.29

0.56 ± 0.38

1

0.00 ± 0.44

ND

p-value

0.285

0.336

1

FBR (%)

EMD + DBBM + CM

0

77.58 ± 6.11

ND

77.58 ± 6.11

ND

EMD + DBBM

0

63.06 ± 8.81

ND

63.06 ± 8.81

ND

p-value

ND

0.066

0.066