Baseline

12 months

p-value

BOP (positive/negative)

EMD + DBBM + CM

7/2

0/9

0.031*

EMD + DBBM

9/0

3/6

ND

p-value^§

ND

0.375*

GI

EMD + DBBM + CM

0.00 ± 0.00 [0, 0, 0]

0.00 ± 0.00 [0, 0, 0]

1^$

EMD + DBBM

0.56 ± 0.73 [0, 0, 2]

0.00 ± 0.00 [0, 0, 0]

0.059^$

p-value^§

0.059^$

1^$

MOB

EMD + DBBM + CM

0.56 ± 053 [0, 1, 1]

0.11 ± 0.33 [0, 0, 1]

0.046^$

EMD + DBBM

0.33 ± 0.50 [0, 0, 1]

0.21 ± 0.10 [0, 0, 1]

0.564^$

p-value^§

0.22^$

0.44^$