Examination

All

n

Control

n

Intervention

n

p

Matrix Metalloproteinase-8 (MMP8) in saliva

Baseline

46.5 (40.2)

42

46.5 (37.7)

18

46.5 (44.0)

24

0.99^b

Week 8

27.5 (28.9)

26.3 (35.2)

30.8 (25.7)

P_{Baseline-Week 8}

0.003^a

0.042^a

0.029^a

0.54^c

Metallopeptidase Inhibitor 1 (TIMP1) in saliva

Baseline

263 (118)

47

270 (128)

22

237 (119)

25

0.72^b

Week 8

225 (111)

257 (110)

214 (104)

P_{Baseline-Week 8}

0.002^a

0.064^a

0.008^a

0.58^c

Interleukin 1β (IL1β) in GCF

Baseline

106 (143)

48

85.7 (83.4)

23

125 (182)

25

0.34^b

Week 8

46.9 (53.2)

56.2 (62.5)

38.3 (42.4)

P_{Baseline-Week 8}

0.009^a

0.13^a

0.029^a

0.44^c

Interleukin 1β (IL1β) in GCF

Baseline

325 (240)

46

310 (266)

22

338 (217)

24

0.72^b

Week 8

181 (142)

201 (152)

163 (133)

P_{Baseline-Week 8}

0.002^a

0.12^a

0.002^a

0.45^c