Assay | Commercial lab 1 (CLIA) | Commercial lab 2 (CLIA) | MI02 Shionogi® BNP (CLEIA) |
Initial concentrations | y = 0.955 x + 6.65 (R2 = 0.994, P < 0.0001) | y = 0.628 x + 1.19 (R2 = 0.989, P < 0.0001) | y = 0.799 x − 0.81 (R2 = 0.990, P < 0.0001) |
Adjusted concentrations (Calibrators contain botha) | y = 1.005 x − 0.96 (R2 = 0.994, P < 0.0001) | y = 0.961 x + 3.67 (R2 = 0.988, P < 0.0001) | y = 0.911 x + 5.49 (R2 = 0.991, P < 0.0001) |
Adjusted concentrations (Calibrators contain only BNP-32) | y = 0.733 x + 0.03 (R2 = 0.995, P < 0.0001) | y = 1.392 x − 13.25 (R2 = 0.989, P < 0.0001) | y = 0.774 x − 1.17 (R2 = 0.990, P < 0.0001) |
Adjusted concentrations (Calibrators contain only glyc proBNP) | y = 1.089 x − 2.97 (R2 = 0.993, P < 0.0001) | y = 0.899 x − 0.43 (R2 = 0.989, P < 0.0001) | y = 0.732 x + 1.30 (R2 = 0.989, P < 0.0001) |