| Characteristics | HIV uninfected caregiver spouses n (%) | HIV uninfected participants n (%) | p value |
| Sadness | 18 (32.7) | 10 (15.9) | 0.032 |
| Pessimism | 15 (27.3) | 9 (14.3) | 0.080 |
| Past failure | 13 (23.6) | 11 (17.5) | 0.406 |
| Loss of pleasure | 16 (29.1) | 10 (15.9) | 0.084 |
| Guilty feelings | 7 (12.7) | 14 (22.2) | 0.179 |
| Punishment feelings | 7 (12.7) | 1 (1.6) | 0.024 |
| Self-dislike | 4 (7.3) | 3 (4.8) | 0.704 |
| Self-criticalness | 10 (18.2) | 6 (9.5) | 0.171 |
| Suicidal thoughts or wishes | 3 (5.5) | 0 (0) | 0.098 |
| Crying | 13 (23.6) | 6 (9.5) | 0.037 |
| Agitation | 12 (21.8) | 10 (16.1) | 0.432 |
| Loss of interest | 10 (18.2) | 6 (9.5) | 0.171 |
| Indecisiveness | 5 (9.1) | 4 (6.3) | 0.732 |
| Worthlessness | 3 (5.6) | 3 (4.8) | 0.846 |
| Loss of energy | 10 (18.2) | 9 (14.3) | 0.566 |
| Changes in sleeping pattern | 9 (16.4) | 10 (15.9) | 0.942 |
| Irritability | 15 (27.3) | 16 (25.4) | 0.817 |
| Changes in appetite | 7 (12.7) | 8 (12.7) | 0.996 |
| Concentration difficulty | 6 (10.9) | 3 (4.8) | 0.301 |
| Tiredness or fatigue | 8 (14.5) | 7 (11.1) | 0.576 |
| Loss of interest in sex | 16 (29.1) | 12 (19.0) | 0.201 |