Authors/Year | Treatment | Result/Observations |
van der Bruggen et al., 2001 DeForge et al., 2004 Domingo et al., 2012 | 4-aminopyridine | There was not benefit. |
Maric, Zorner and Dietz, 2008 Domingo et al., 2012 | Levodopa | No difference between placebo and medication. |
Domingo et al., 2012 | Clonidine | Improvement in walking scores. |
Cyproheptadine | Walking speed increased; Improved muscle coordination; Decreased clonus. | |
Cyproheptadine + Clonidine | Decreased clonus; Muscle activity of the lower limbs increased. | |
Geisler et al., 2001 Domingo et al., 2012 | Ganglioside GM-1 | Increased motor scores; Walking distance and speed increased. |
Domingo et al., 2012 | Baclofen | Improves motor scores. |
Qian et al., 2005 Domingo et al., 2012 Nejati-Koshki K., et al., 2017 | Methylprednisolone | Neuroprotective; Anti-inflammatory; Attenuation of lipid peroxidation; Myopathies and other complications. |
Liu-Snyder, P. et al., 2006 Hamann K. et al., 2007 Hamann, K. & Shi, R., 2009 | Hydralazine | Neuroprotection against acrolein; Injury reversal. |