Parameters 1	Drug product 2	API combination 3
	Cladribine
absorption	k_a = 0.014 h⁻¹	k_a = 1.5 h⁻¹
	t_1/2_a = 49.5 h	t_1/2a = 0.46 h
	С_max = 6.0 mcg/ml	С_max = 19.0 mcg/ml
	C₀ = 276.4 mcg/ml	C₀ = 3.2 mcg/ml
Distribution and accumulation	V_d = 0.54 l/kg	V_d = 46.7 l/kg
	V_ss = 9.93 l/kg	V_ss = 7.8 l/kg
	AUC = 30.7 mcg·h/ml	AUC = 43.9 mcg·h/ml
elimination	k_e = 1.11 h⁻¹	k_e = 0.63 h⁻¹
	t_1/2_e = 0.62 h	t_1/2_e = 1.11 h
	Cl = 4.89 ml/h	Cl = 3.42 ml/h
	MRT = 2.03 h	MRT = 2.3 h
bioavailability of Cladribine (f) in the claimed drug product composition, 70%
	Ribavirin
absorption	k_a = 0.972 h⁻¹	k_a = 8.99 h⁻¹
	t_1/2a = 0.713 h	t_1/2a = 0.077 h
	С_max = 75.5 mcg/ml	С_max = 209.8 mcg/ml
	C₀ = 115.6 mcg/ml	C₀ = 172.37 mcg/ml
Distribution and accumulation	V_d = 1.298 l/kg	V_d = 0.870 l/kg
	V_ss = 1.635 l/kg	V_ss = 1.138 l/kg
	AUC = 504.24 mcg·h/ml	AUC = 1275.13 mcg·h/ml
elimination	k_e = 0.213 h⁻¹	k_e = 0.105 h⁻¹
	t_1/2e = 3.25 h	t_1/2e = 6.6 h
	Cl = 0.300 ml/h	Cl = 0.118 ml/h
	MRT = 5.45 h	MRT = 9.64 h
bioavailability of Ribavirin (f) in the claimed drug product composition, 40%