Incubation

0

5

10

15

20

25 (µM)

4

1.11 ± 0.16

3.41 ± 0.41a

3.51 ± 0.24a

3.69 ± 0.38a

4.99 ± 0.24a

4.07 ± 0.24a

6

1.09 ± 0.03

4.74 ± 0.99

4.98 ± 0.50b

6.78 ± 0.46b

9.79 ± 0.87b

11.34 ± 1.32b

18

1.11 ± 0.12

5.40 ± 0.11b

6.24 ± 0.23c

6.19 ± 0.63b

10.48 ± 1.15c

12.80 ± 0.75c

24

1.17 ± 0.05

6.57 ± 0.21c

7.74 ± 0.19d

7.92 ± 0.34c

11.14 ± 0.62d

14.14 ± 0.54d