| Characteristic | Total | Severity stage | p | Outcome of the disease | p | ||
| Not serious | Serious | Healed | Deceased | ||||
| Uremia (n) | 561 | 465 | 96 |
| 499 | 62 |
|
| Median (g/L) [IQR] | 0.2 [0.2 - 0.3] | 0.2 [0.2 - 0.3] | 0.4 [0.3 - 0.9] | <0.001 | 0.2 [0.2 - 0.3] | 0.6 [0.3 - 1.5] | <0.001 |
| High n (%) | 77 (13.7) | 35 (7.5) | 42 (43.8) | <0.001 | 42 (8.4) | 35 (56.5) | <0.001 |
| Serum creatinine (n) | 506 | 413 | 93 |
| 447 | 59 |
|
| Median (mg/L) [IQR] | 10 [9 - 12] | 10 [8 - 12] | 12.2 [9 - 22] | <0.001 | 10 [8 - 12] | 14 [9 - 48] | <0.001 |
| High n (%) | 57 (11.3) | 23 (5.6) | 34 (36.6) | <0.001 | 28 (6.3) | 29 (49.2) | <0.001 |
| AST | 565 | 482 | 83 |
| 514 | 51 |
|
| Median (IU/L) [IQR] | 38 [28.0 - 56.7] | 36 [27 - 50] | 62 [44 - 108] | <0.001 | 36 [28 - 52] | 65 [43 - 173] | <0.001 |
| High n (%) | 142 (25.1) | 96 (19.9) | 46 (55.4) | <0.001 | 112 (21.8) | 30 (58.8) | <0.001 |
| ALT (n) | 565 | 482 | 83 |
| 514 | 51 |
|
| Median (IU/L) [IQR] | 30 [20.2 - 45.0] | 28.5 [20 - 44] | 41 [26 - 74] | <0.001 | 29 [20 - 45] | 41 [24 - 71] | <0.001 |
| High n (%) | 91 (16.1) | 62 (12.9) | 29 (34.9) | <0.001 | 74 (14.4) | 17 (33.3) | 0.040 |
| GGT (n) | 391 | 340 | 51 |
| 359 | 32 |
|
| Median (IU/L) [IQR] | 39 [24 - 76] | 35 [23 - 62.5] | 79 [49 - 177] | <0.001 | 36 [23 - 66] | 80.5 [58.5 - 195] | <0.001 |
| High n (%) | 95 (24.3) | 69 (20.3) | 26 (51.0) | <0.001 | 77 (21.4) | 18 (56.3) | <0.001 |
| ALP (n) | 74 | 48 | 26 |
| 61 | 13 |
|
| Median (IU/L) [IQR] | 91 [69 - 163] | 91 [67.5 - 159.5] | 95.5 [75 - 164] | 0.575 | 91 [73 - 163] | 100 [65 - 163] | 0.847 |
| High n (%) | 3 (4.1) | 2 (4.2) | 1 (3.8) | 0.946 | 1 (1.6) | 2 (15.4) | 0.052 |
| TC (n) | 374 | 317 | 57 |
| 342 | 32 |
|
| Median (g/L) [IQR] | 1.7 [1.4 - 2.0] | 1.8 [1.5 - 2.1] | 1.7 [1.3 - 2.0] | 0.065 | 1.8 [1.5 - 2.1] | 1.5 [1.2 - 2.0] | 0.016 |
| Hypo-TC n (%) | 79 (21.1) | 61 (19.2) | 18 (31.6) | 0.035 | 64 (18.7) | 15 (46.9) | 0.020 |
| Hyper-TC n (%) | 52 (13.9) | 47 (14.8) | 5 (8.8) | 0.224 | 48 (14) | 4 (12.5) | 0.810 |
| HDL-c (n) | 205 | 174 | 31 |
| 190 | 18 |
|
| Median (g/L) [IQR] | 0.5 [0.4 - 0.6] | 0.5 [0.4 - 0.6] | 0.4 [0.2 - 0.6] | 0.006 | 0.5 [0.4 - 0.6] | 0.3 [0.2 - 0.4] | <0.001 |
| Hypo-HDL-c n (%) | 42 (20.5) | 26 (14.9) | 16 (51.6) | <0.001 | 1.1 [0.8 - 1.4] | 0.7 [0.4 - 1.0] | <0.001 |
| LDL-c (n) | 208 | 177 | 31 |
| 190 | 18 |
|
| Median (g/L) [IQR] | 1.07 [0.7 - 1.3] | 1.1 [0.7 - 1.3] | 0.8 [0.4 - 1.2] | 0.001 | 1.1 [0.8 - 1.4] | 0.7 [0.4 - 1.0] | <0.001 |
| Hyper-LDL-c n (%) | 27 (13) | 25 (14.1) | 2 (6.5) | 0.241 | 25 (14.1) | 2 (6.5) | 0.241 |
| TG (n) | 352 | 297 | 55 |
| 320 | 32 |
|
| Median (g/L) [IQR] | 0.9 [0.7 - 1.4] | 0.9 [0.7 - 1.3] | 1.4 [0.9 - 2] | <0.001 | 1 [0.7 - 1.4] | 1.3 [0.9 - 2.3] | <0.001 |
| Hypo-TG n (%) | 29 (8.2) | 25 (8.4) | 4 (7.3) | 0.776 | 27 (8.4) | 2 (6.3) | 0.667 |
| High n (%) | 58 (16.5) | 37 (12.5) | 21 (38.2) | <0.001 | 43 (13.4) | 15 (46.9) | <0.001 |
| Natremia (n) | 180 | 115 | 65 |
| 140 | 40 |
|
| Median (mmol/L) [IQR] | 140 [136.2 - 143.6] | 141 [137 - 144] | 139 [136 - 142.4] | 0.268 | 140 [137 - 143] | 140 [135 - 146] | 0.558 |
| Hyponatremia n (%) | 22 (12.2) | 13 (11.3) | 9 (13.8) | 0.617 | 13 (9.3) | 9 (22.5) | 0.024 |
| Chloremia (n) | 192 | 123 | 69 |
| 151 | 41 |
|
| Median (mmol/L) [IQR] | 102 [98 - 105] | 102 [99 - 105] | 100 [94 - 105] | 0.022 | 102 [98 - 105] | 101.5 [95 - 106] | 0.773 |
| Hypochloremia n (%) | 46 (24%) | 22 (17.9) | 24 (34.8) | 0.008 | 33 (21.9) | 13 (31.7) | 0.189 |
| Hyperchloremia n (%) | 35 (18.2) | 23 (18.7) | 12 (17.4) | 0.821 | 25 (16.6) | 10 (24.4) | 0.249 |
| Kalemia (n) | 192 | 123 | 69 |
| 151 | 41 |
|
| Median (mmol/L) [IQR] | 4.4 [3.99 - 4.8] | 4.4 [4 - 4.8] | 4.3 [3.9 - 4.8] | 0.450 | 4.4 [3.9 - 4.7] | 4.6 [4 - 5.1] | 0.094 |
| Hypokalemia n (%) | 10 (5.2) | 4 (3.3) | 6 (8.7) | 0.103 | 8 (5.3) | 2 (4.9) | 0.914 |
| Hyperkalemia n (%) | 18 (9.4) | 12 (9.8) | 6 (8.7) | 0.808 | 11 (7.3) | 7 (17.1) | 0.056 |
| Calcemia (n) | 114 | 97 | 17 |
| 104 | 10 |
|
| Median (mg/L) [IQR] | 91 [86 - 98.5] | 93 [88 - 99] | 85 [83 - 90] | 0.001 | 92 [87 - 99] | 82.5 [81 - 89] | <0.001 |
| Hypocalcemia n (%) | 47 (41.2) | 35 (36.1) | 12 (70.6) | 0.007 | 39 (37.5) | 8 (80) | 0.009 |
| Hypercalcemia n (%) | 4 (3.5) | 4 (4.1) | 0 (0) | 0.394 | 4 (3.8) | 0 (0) | 0.527 |
| Magnesemia (n) | 98 | 88 | 10 |
| 96 | 02 |
|
| Median (mg/L) [IQR] | 20 [18 - 22] | 19.5 [17 - 22] | 19.5 [18 - 22] | 0.953 | 19 [17 - 22] | 20.5 [20 - 21] | 0.659 |
| Hypomagnesemia n (%) | 15 (15.3) | 13 (14.8) | 8 (80) | 0.663 | 15 (15.6) | 0 (0) | 0.543 |
| Hypermagnesemia n (%) | 1 (1) | 1 (1.1) | 0 (0) | 0.734 | 1(1) | 0 (0) | 0.884 |
| CRP (n) | 134 | 92 | 42 |
| 113 | 21 |
|
| Median (mg/L) [IQR] | 12 [6 - 48] | 6 [6 - 25.5] | 36 [12 - 96] | <0.001 |
|
|
|
| High n (%) | 80 (59.7) | 44 (47.8) | 36 (85.7) | <0.001 | 63 (55.8) | 17 (81.0) | 0.036 |
| Blood glucose (n) | 548 | 464 | 84 |
| 493 | 55 |
|
| Median (g/L) [IQR] | 0.9 [0.8 - 1.2] | 0.9 [0.8 - 1.2] | 1.2 [0.9 - 1.9] | <0.001 |
|
|
|
| Hypoglycemia n (%) | 5 (0.9) | 3 (0.3) | 2 (2.4) | 0.124 | 3 (0.6) | 2 (3.6) | 0.025 |
| Hyperglycemia n (%) | 183 (33.4) | 133 (28.7) | 50 (59.7) | <0.001 | 149 (30.2) | 34 (61.8) | <0.001 |
| HbA1c (n) | 71 | 52 | 19 |
| 59 | 12 |
|
| Median (mg/L) [IQR] | 7.3 [5.8 - 9.4] | 7.4 [5.8 - 9.6] | 6.4 [5.9 - 9.1] | 0.550 | 7.4 [6 - 9.6] | 6.3 [5.2 - 9.2] | 0.211 |
| High n (%) | 41 (57.7) | 32 (61.5) | 9 (47.4) | 0.284 | 36 (61.0) | 5 (41.7) | 0.216 |