Fibrosis test

Calculation

P2/MS

[Platelet count (109/L)]²/[monocyte fraction (%) _segmented neutrophil fraction (%)]

AAR

AST/ALT

API

Age (years): <30 = 0; 30 - 39 = 1; 40 - 49 = 2; 50 - 59 = 3; 60 - 69 = 4; ≥70 = 5

Platelet count (109/L): ≥225 = 0; 200 - 224 = 1; 175 - 199 = 2; 150 - 174 = 3;

125 - 149 = 4; <125 = 5 AP index is the sum of the above (possible value 0 - 10)

APRI

[(AST/ULN)/platelet count (109/L)]_100

SPRI

Spleen size (cm)/platelet count (109/L)_100

ASPRI

Age (years): <30 = 0; 30 - 39 = 1; 40 - 49 = 2; 50 - 59 = 3; 60 - 69 = 4; ≥70 = 5

ASPRI is the sum of age and SPRI

Formula by Berzigotti et al. (16)

Risk score = [−0.193+ (−0.359 × albumin) + (16.456 × INR) + (−0.016 × ALT)].

Our discovered formula

Final equation= e*/1 + e*

Where * = −5.192 + (0.086 × segmented neutrophils) + (0.381 × monocytes) − (0.04 × platelet) + (0.637 × T. bilirubin)

And e = exponential