| Univariate | Multivariate | ||||
Limited disease:a | HR | 95% CI | P | HR | 95% CI | P |
Gender |
|
|
|
|
|
|
Female (n = 49) | 1.00 | ref |
| 1.00 | ref |
|
Male (n = 59) | 2.10 | 1.37 - 3.22 | 0.0007 | 2.43 | 1.45 - 4.06 | 0.0007 |
|
|
|
|
|
|
|
Age |
|
|
|
|
|
|
<70 (n = 68) | 1.00 | ref |
| 1.00 | ref |
|
≥70 (n = 40) | 1.64 | 1.08 - 2.48 | 0.020 | 1.07 | 0.64 - 1.77 | 0.804 |
|
|
|
|
|
|
|
Performance status |
|
|
|
|
|
|
0-1 (n = 74) | 1.00 | ref |
| 1.00 | ref |
|
2-4 (n = 34) | 2.01 | 1.29 - 3.11 | 0.002 | 2.18 | 1.17 - 4.06 | 0.014 |
|
|
|
|
|
|
|
Extensive disease:b |
|
|
|
|
|
|
Gender |
|
|
|
|
|
|
Female (n = 56) | 1.00 | ref |
| 1.00 | ref |
|
Male (n = 102) | 1.62 | 1.15 - 2.28 | 0.006 | 1.59 | 1.12 - 2.26 | 0.010 |
|
|
|
|
|
|
|
Age |
|
|
|
|
|
|
<70 (n = 80) | 1.00 | ref |
| 1.00 | ref |
|
≥70 (n = 78) | 1.28 | 0.93 - 1.77 | 0.133 | 0.67 | 0.45 - 0.99 | 0.046 |
|
|
|
|
|
|
|
Performance status |
|
|
|
|
|
|
0-1 (n = 42) | 1.00 | ref |
| 1.00 | ref |
|
2-4 (n = 116) | 2.42 | 1.67 - 3.50 | <0.001 | 2.48 | 1.63 - 3.77 | <0.001 |